? Credit Points : 10  ? SCQF Level : 10  ? Acronym : MED-4-PHntmx2

The Neurotransmitter Mechanisms B course will be organised and examined as a pair with Neurotransmitter Mechanisms A. By reference to important topical issues in cellular neuropharmacology the course aims to examine receptor mechanisms underlying 'fast' excitatory and inhibitory synaptic transmission in the central nervous system mediated by ionotropic receptors. In addition the course will also discuss the types of signal transduction pathways used by different receptor types to modulate ion channel function. The interpretation of structure-function studies of ligand-gated ion channel function will be discussed and the use of kinetic schemes to describe agonist action will be covered. The course will be delivered through a co-ordinated programme of lectures, tutorials and student-led problem solving sessions. Laboratory work forms an integral component of the course. Computer simulations of equivalent circuitry and cell model practicals coupled with 'real-life' electrophysiological recordings will be used to illustrate the principles of receptor activation and neuronal excitability. The material covered in the lecture and practical components will emphasize how the use of electrophysiological recording techniques continues to further our understanding of synaptic transmission.

? This course is not available to visting students.

? Pre-requisites : Permission of the Curriculum Approval Officer. Pharmacology 3. Physiology is recommended

? Co-requisites : Nature of Receptors Core Course. Neurotransmitter Mechanisms A.

? Prohibited combinations : Ion Channels in Health and Disease.

Home subject area

BSc Honours (Medicine), (Medicine, Schedule R)

Other subject areas

Pharmacology, (School of Biological Sciences, Schedule K)

? Normal year taken : 4th year

? Delivery Period : Semester 1 (Blocks 1-2)

? Contact Teaching Time : 2 hour(s) 45 minutes per week for 11 weeks

First Class Information

Date Start End Room Area Additional Information 22/09/2005 09:00 : Room G.8, 1 George Square (Neuroscience) Med+Vet

All of the following classes

Type Day Start End Area Lecture Friday 09:00 17:00 Med+Vet

Increased undertanding of biological processes.
Detailed learningoutcomes will be provided later.

100% Written Examination.

Exam times

Diet Diet Month Paper Code Paper Name Length 1ST December 1 - 1 hour(s) 30 minutes

The Course Secretary should be the first point of contact for all enquiries.

Course Secretary

Mrs Patricia Anne Law
Tel : (0131 6)50 3161
Email : Anne.Law@ed.ac.uk

Course Organiser

Dr HJ Olverman
Tel : (0131 6)50 3523
Email : H.Olverman@ed.ac.uk

School Website : http://www.mvm.ed.ac.uk/

College Website : http://www.mvm.ed.ac.uk/