Postgraduate Course: Genomics and Pathway Biology I (LISC11058)
Course Outline
| School |
School of Clinical Sciences and Community Health |
College |
College of Medicine and Veterinary Medicine |
| Course type |
Standard |
Availability |
Available to all students |
| Credit level (Normal year taken) |
SCQF Level 11 (Postgraduate) |
Credits |
40 |
| Home subject area |
Life Sciences |
Other subject area |
None |
| Course website |
http://www.gti.ed.ac.uk |
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| Course description |
Post genomics continues to be a rapidly evolving field. This is particularly true in the mapping and modelling of biological systems using datasets from high throughput genomic, proteomic and imaging experiments. Sophisticated modelling and analytical methods are being developed via an interdisciplinary approach involving biologists, bioinformatics, computational and physical sciences. The mapping and interpretation of biological pathways and networks is critical for a more complete understanding of biological systems relevant to disease and development. In order to achieve this, it is becoming increasingly possible to derive sophisticated biological pathways and networks from high throughput genomic (transcriptomic and RNA interference), proteomic and imaging data.
The course will run in semester 1 and will provide an important new component that will complement and greatly strengthen the current MSc genomics programme run by the GTI.
The course will provide (1) an introduction to the genetic pathways underpinning development, normal function and disease, together with the tools for mapping them formally, (2) seminar presentations and discussion by the students on important papers associated with pathways, and (3) 12-week mini projects on pathways biology which may be either laboratory-based or involve computational work.
Seminars and lectures will be held twice weekly. Topics will include:
- Introductory sessions on pathway mapping and analysis.
- Outline of IT technologies and systems for generating and interpreting biological networks
- Data integration and use of ontologies in pathway and network modelling
- Exploring through seminar work important examples of biological networks, including:
- Viral-host interactions
- The interferon regulatory network
- Modelling of the tumour necrosis factor network
- Systems biology of the macrophage
- Modelling of tissue specific gene expression in disease and development
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Entry Requirements
| Pre-requisites |
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Co-requisites |
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| Prohibited Combinations |
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Other requirements |
None
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| Additional Costs |
None |
Course Delivery Information
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| Delivery period: 2010/11 Semester 1, Available to all students (SV1)
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WebCT enabled: No |
Quota: None |
| Location |
Activity |
Description |
Weeks |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
| No Classes have been defined for this Course |
| First Class |
First class information not currently available |
Summary of Intended Learning Outcomes
- provide students with thorough and specific preparation for 3 year PhD training in the life sciences;
- award an MSc by Research en route to the PhD;
provide an opportunity, if necessary or desirable, to exit from research training at the end of Year 1 with an Edinburgh Masters or Diploma by Research Degree |
Assessment Information
| One 10 week mini project write-up (5000 words) = 100% |
| Please see Visiting Student Prospectus website for Visiting Student Assessment information |
Special Arrangements
| Not entered |
Contacts
| Course organiser |
Dr Douglas Roy
Tel: (0131) 242 6279
Email: Douglas.Roy@ed.ac.uk |
Course secretary |
Mrs Marie Manson
Tel: (0131 6)50 3723
Email: Marie.Manson@ed.ac.uk |
|
copyright 2010 The University of Edinburgh -
1 September 2010 6:16 am
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