Postgraduate Course: Commercial Aspects of Drug Discovery (PGBI11049)
Course Outline
School |
School of Biological Sciences |
College |
College of Science and Engineering |
Course type |
Standard |
Availability |
Available to all students |
Credit level (Normal year taken) |
SCQF Level 11 (Postgraduate) |
Credits |
10 |
Home subject area |
Postgraduate |
Other subject area |
None |
Course website |
None |
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Course description |
This course gives the student a general, illustrated overview over the different stages in drug design from the industrial perspective. The considerations and practicalities of selecting, initiating and running a drug discovery programme will be covered as well as the key topic of finding a lead compound that exhibits the desired biological activity with the highest possible benefits. This course is clearly distinct from the structure-based drug design compulsory module where the topic of rational drug design is covered in detail. The course includes industrial visits and visits from industrial scientists. |
Entry Requirements
Pre-requisites |
It is RECOMMENDED that students have passed
Pharmacology (DENT11002)
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Co-requisites |
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Prohibited Combinations |
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Other requirements |
None
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Additional Costs |
None |
Course Delivery Information
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Delivery period: 2010/11 Semester 2, Available to all students (SV1)
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WebCT enabled: Yes |
Quota: None |
Location |
Activity |
Description |
Weeks |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
External To University | Lecture | | 1-11 | 09:00 - 17:00 | | | | |
First Class |
First class information not currently available |
Summary of Intended Learning Outcomes
Appreciation of various aspects in the drug discovery process, including industrial considerations and the drug testing process.
- Principles of drug action, general topics in medicinal chemistry
- Industrial considerations for picking a drug area (Existing therapies, commercial aspects, etc)
- Lead compounds
Gene profiling
Natural products
Synthetic products
Screening methods: Assays, Microarrays
Libraries, combinatorial chemistry
Rational design (structure-based drug design, etc)
- Assessing lead compounds
Absorption, distribution, metabolism, excretion and toxicology (ADME/tox)
In vitro and in vivo testing
- Drug delivery
- Clinical trials
- Production and marketing
Drug synthesis
Marketing, social, moral aspects
Patents
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Assessment Information
A 'Blog' account of each of the sessions. PLUS an essay covering synthesis of drug commercialisation obtained from the visits and outside reading. |
Please see Visiting Student Prospectus website for Visiting Student Assessment information |
Special Arrangements
Not entered |
Contacts
Course organiser |
Prof Malcolm Walkinshaw
Tel: (0131 6)50 3719
Email: M.Walkinshaw@ed.ac.uk |
Course secretary |
Miss Vicky Mactaggart
Tel: (0131 6)51 7052
Email: Vicky.Mactaggart@ed.ac.uk |
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copyright 2010 The University of Edinburgh -
1 September 2010 6:24 am
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