Undergraduate Course: Synthetic Organic Chemistry Level 11 (CHEM11026)

Course Outline
School	School of Chemistry	College	College of Science and Engineering
Course type	Standard	Availability	Available to all students
Credit level (Normal year taken)	SCQF Level 11 (Year 4 Undergraduate)	Credits	20
Home subject area	Chemistry	Other subject area	None
Course website	None	Taught in Gaelic?	No
Course description	A lecture course covering contemporary synthetic methods in organic chemistry, and their application to complex molecule synthesis. The course comprises individual lecture courses on: Reagents for Organic Synthesis, Synthesis of Natural Products, Solid Phase Synthesis, Synthesis of Unnatural Products, Pericyclic Reactions, Organometallics in Synthesis. Either the Level 10 or Level 11 version of this course (as specified in the degree programme tables) is a compulsory requirement for Year 4/5 students on degrees in Chemistry or Medicinal and Biological Chemistry, but can be taken by Year 4/5 students on any Chemistry degree programme.

Entry Requirements (not applicable to Visiting Students)
Pre-requisites	Students MUST have passed: Chemistry 3A (CHEM09005) AND Chemistry 3B (CHEM09006) AND Chemistry 3P Practical and Transferable Skills (CHEM09007)	Co-requisites
Prohibited Combinations	Students MUST NOT also be taking Synthetic Organic Chemistry Level 10 (CHEM10024)	Other requirements	Must include a weighted average of Grade C or higher in all Chemistry 3 courses AND a weighted average of Grade D or higher in Chemistry 3A and Chemistry 3B, at the first attempt and Mathematics qualifications of at least 20 credits to level Applicable Mathematics 1 and Mathematical Methods 1; or with the permission of Head of School.
Additional Costs	None

Information for Visiting Students
Pre-requisites	None
Displayed in Visiting Students Prospectus?	Yes

Course Delivery Information

Delivery period: 2011/12 Semester 1, Available to all students (SV1)						WebCT enabled: No		Quota: None
Location	Activity	Description	Weeks	Monday	Tuesday	Wednesday	Thursday	Friday
King's Buildings	Lecture		1-11			09:00 - 09:50
King's Buildings	Lecture		1-11					09:00 - 09:50
King's Buildings	Lecture		1-11		09:00 - 09:50
First Class	Week 1, Tuesday, 09:00 - 09:50, Zone: King's Buildings. T100
Additional information	30 hours lectures + 6 hours tutorials, at times arranged.
Exam Information
Exam Diet	Paper Name		Hours:Minutes
Main Exam Diet S2 (April/May)			3:00

Delivery period: 2011/12 Semester 1, Part-year visiting students only (VV1)						WebCT enabled: Yes		Quota: None
Location	Activity	Description	Weeks	Monday	Tuesday	Wednesday	Thursday	Friday
King's Buildings	Lecture		1-11		09:00 - 09:50
King's Buildings	Lecture		1-11			09:00 - 09:50
King's Buildings	Lecture		1-11					09:00 - 09:50
First Class	Week 1, Tuesday, 09:00 - 09:50, Zone: King's Buildings. T100
Additional information	30 hours lectures + 6 hours tutorials, at times arranged.
Exam Information
Exam Diet	Paper Name		Hours:Minutes
Main Exam Diet S1 (December)			3:00

Summary of Intended Learning Outcomes
At the end of this course students will be able to: - discuss the chemistry and applications of a range of phosphorus, silicon, sulfur and selenium reagents in modern organic synthesis - compare and contrast the biosynthesis of natural products with their chemical synthesis in the laboratory - discuss the relative merits of solid phase and solution phase organic synthesis - understand the role of solid phase organic synthesis in the pharmaceutical industry, particularly with respect to the use of combinatorial chemistry in screening against biological targets - discuss the synthesis of various functional molecular architectures and the principles behind molecular switches, motors, shuttles and other 'designer' molecules - apply Frontier Molecular Orbital (FMO) theory to predict the results of electrocyclic, cycloaddition and sigmatropic rearrangement processes - compare and contrast mechanistic details of common modern synthetic organometallic reactions - predict the outcome of some simple transition metal catalysed processes and comment on the strategies used by others for the synthesis of more complex targets Learning outcomes specific to attainment of a pass at Level 11 include: - ability to integrate all, or most, of the main areas of the course - development of original and creative responses to problems and issues within the course - application of critical analysis, evaluation and synthesis to issues at the forefront of the subject area

Assessment Information
One degree exam of 3 hours. (Visiting Student Variant Assessment One degree exam of 3 hours at the end of Semester 1.)

Special Arrangements
None

Contacts
Course organiser	Dr Paul Lusby Tel: Email: Paul.Lusby@ed.ac.uk	Course secretary	Ms Sarah Mcneil Tel: (0131 6)50 4707 Email: Sarah.F.McNeil@ed.ac.uk