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DEGREE REGULATIONS & PROGRAMMES OF STUDY 2011/2012
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DRPS : Course Catalogue : School of Biomedical Sciences : Physiology (Biomedical Sciences)

Undergraduate Course: Mechanisms of Forebrain Development (PYBM10029)

Course Outline
SchoolSchool of Biomedical Sciences CollegeCollege of Medicine and Veterinary Medicine
Course typeStandard AvailabilityNot available to visiting students
Credit level (Normal year taken)SCQF Level 10 (Year 4 Undergraduate) Credits10
Home subject areaPhysiology (Biomedical Sciences) Other subject areaNone
Course website None Taught in Gaelic?No
Course descriptionThe embryonic forebrain gives rise to several structures including the cerebral cortex which is important for all higher cognitive functions unique to humans. Cortical malformations are thought to cause a number of cognitive diseases including mental retardation, epilepsy, autism and schizophrenia. This course will explore the molecular and cellular mechanisms which underlie the normal and abnormal formation of forebrain structures. It will address how signalling pathways and transcription factors interact to pattern the forebrain, the characteristics of embryonic and adult stem cells and how migration and axon pathfinding defects result in cognitive disorders of the cerebral cortex.
Entry Requirements (not applicable to Visiting Students)
Pre-requisites Co-requisites
Prohibited Combinations Other requirements None
Additional Costs None.
Course Delivery Information
Delivery period: 2011/12 Semester 1, Not available to visiting students (SS1) WebCT enabled:  Yes Quota:  None
Location Activity Description Weeks Monday Tuesday Wednesday Thursday Friday
CentralLecture1-11 14:00 - 17:00
First Class Week 1, Tuesday, 14:00 - 17:00, Zone: Central. Biomedical Seminar Room 6, BMTO, Doorway 3, Old Medical School, Teviot Place
Exam Information
Exam Diet Paper Name Hours:Minutes
Main Exam Diet S1 (December)Mechanisms of Forebrain Development1:30
Summary of Intended Learning Outcomes
Demonstrate knowledge and understanding of:
Determinants controlling forebrain patterning;
The roles of a wide range of different cellular processes (proliferation, differentiation, migration, axon pathfinding) involved in cortical development;
How abnormal processes can lead to cognitive disorders

Demonstrate an ability to:
Take a critical approach to different models, concepts and approaches to forebrain development.
Make constructive use of research and theory to design and plan projects in forebrain development.
Take an informed part in debate about issues with current concepts of forebrain development.
Assessment Information
100% Written exam
Special Arrangements
None
Additional Information
Academic description Not entered
Syllabus Not entered
Transferable skills Not entered
Reading list Not entered
Study Abroad Not entered
Study Pattern Not entered
KeywordsPHYSMechfordev
Contacts
Course organiserDr Mike Ludwig
Tel: (0131 6)50 3275
Email: Mike.Ludwig@ed.ac.uk
Course secretaryMs Victoria Farrar
Tel: (0131 6)50 3717
Email: v.farrar@ed.ac.uk
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© Copyright 2011 The University of Edinburgh - 16 January 2012 6:44 am