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DEGREE REGULATIONS & PROGRAMMES OF STUDY 2013/2014
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DRPS : Course Catalogue : School of Biological Sciences : Postgraduate

Postgraduate Course: Next Generation Genomics (BILG11004)

Course Outline
SchoolSchool of Biological Sciences CollegeCollege of Science and Engineering
Course typeStandard AvailabilityNot available to visiting students
Credit level (Normal year taken)SCQF Level 11 (Postgraduate) Credits10
Home subject areaPostgraduate Other subject areaNone
Course website None Taught in Gaelic?No
Course descriptionThis course will introduce next generation genomics technologies, and guide students through the bioinformatics analysis of data across the wide range of applications possible (from genome sequencing, so small RNA discovery, to expression quantification).
There will be a particular focus on building understanding of the algorithms used in the bioinformatics analyses, and of the interplays between genetic variability, genome complexity and experimental and statistics noise.
Entry Requirements (not applicable to Visiting Students)
Pre-requisites Co-requisites
Prohibited Combinations Other requirements None
Additional Costs None
Course Delivery Information
Delivery period: 2013/14 Semester 2, Not available to visiting students (SS1) Learn enabled:  Yes Quota:  None
Web Timetable Web Timetable
Course Start Date 13/01/2014
Breakdown of Learning and Teaching activities (Further Info) Total Hours: 100 ( Lecture Hours 30, Summative Assessment Hours 3, Programme Level Learning and Teaching Hours 2, Directed Learning and Independent Learning Hours 65 )
Additional Notes
Breakdown of Assessment Methods (Further Info) Written Exam 50 %, Coursework 50 %, Practical Exam 0 %
Exam Information
Exam Diet Paper Name Hours & Minutes
Main Exam Diet S2 (April/May)Next Generation Genomics3:00
Summary of Intended Learning Outcomes
On successfully completing the course, students will be able to demonstrate an understanding of the molecular biology and technological underpinnings of next-generation sequencing, be conversant with the core algorithms used in data analyses, and aware of the many applications for which the technologies. They will be able to choose in an informed way, the best analytical solutions for particular problems, and have an overview of the landscape of advances in genomics and genome-scale data analysis.
Assessment Information
The course will be assessed by:
(a) an in-course assessment esssay (based on literature review of a selected topic in next-generation genomics bioinformatics) (worth 50%)
(b) an essay-based exam paper (worth 50%)
Special Arrangements
None
Additional Information
Academic description Not entered
Syllabus The course will cover the following topic areas, through delivered lectures, class discussion, tutorials, and hands-on practicals:

- Introduction to the technologies of next generation sequencing
- Investigating genome variability, gene expression, gene regulation and genome structure by mapping sequences to a reference genome
- Assembling genome and transcriptome sequences de novo from next generation sequencing data
- The future prospects: the third generation of sequencing technologies, and the bioinformatics challenges they propose.
Transferable skills Not entered
Reading list Not entered
Study Abroad Not entered
Study Pattern Not entered
KeywordsNGG
Contacts
Course organiserDr Karim Gharbi
Tel:
Email: karim.gharbi@ed.ac.uk
Course secretaryMiss Vicky Mactaggart
Tel: (0131 6)51 7052
Email: Vicky.Mactaggart@ed.ac.uk
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