Undergraduate Course: Biomacromolecules Level 11 (CHEM11043)
Course Outline
| School | School of Chemistry |
College | College of Science and Engineering |
| Course type | Standard |
Availability | Available to all students |
| Credit level (Normal year taken) | SCQF Level 11 (Year 4 Undergraduate) |
Credits | 20 |
| Home subject area | Chemistry |
Other subject area | None |
| Course website |
None |
Taught in Gaelic? | No |
| Course description | A course of lectures and a workshop covering synthesis, chemistry, structure, function and engineering of biological polymers. The course will teach how biopolymers are constructed from simple building blocks, and folded into three-dimensional structures. The ability of biomacromolecules to dynamically and specifically interact and cooperate with one another, on a range of timescales and affinities, will be discussed. The course will also cover production of modified or engineered biomacromolecules. Chemical complexity and functional capabilities arising from prosthetic groups, cofactors, metal ions and post-translational modifications will be described as will the ability of proteins to act as molecular wires and biological catalysts. The taught material will include components on protein manufacture and validation, protein and nucleic acid chemistry, enzymology, metalloproteins, and the role of proteins in cellular electrochemistry.
Either the Level 10 or Level 11 version of this course version of this course (as specified in the degree programme tables) is a compulsory requirement for Year 4/5 students on degrees in Medicinal and Biological Chemistry, but can be taken by Year 4/5 students on any Chemistry degree programme.
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Information for Visiting Students
| Pre-requisites | None |
| Displayed in Visiting Students Prospectus? | No |
Course Delivery Information
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| Delivery period: 2013/14 Semester 1, Available to all students (SV1)
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Learn enabled: Yes |
Quota: None |
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Web Timetable |
Web Timetable |
| Course Start Date |
16/09/2013 |
| Breakdown of Learning and Teaching activities (Further Info) |
Total Hours:
200
(
Lecture Hours 30,
Seminar/Tutorial Hours 9,
Summative Assessment Hours 3,
Revision Session Hours 6,
Programme Level Learning and Teaching Hours 4,
Directed Learning and Independent Learning Hours
148 )
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| Additional Notes |
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| Breakdown of Assessment Methods (Further Info) |
Written Exam
100 %,
Coursework
0 %,
Practical Exam
0 %
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| Exam Information |
| Exam Diet |
Paper Name |
Hours & Minutes |
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| Main Exam Diet S2 (April/May) | | 3:00 | |
Summary of Intended Learning Outcomes
Upon completion of this course students should be able to:
- explain the biosynthesis as well as the laboratory-based manufacture and purification of biologically important polymers.
- appreciate how knowledge of macromolecular 3D structure illuminates the understanding of mechanism and how (with examples) "form follows function".
- understand, through the study of examples, the principles of molecular recognition and cooperation, molecular crowding and self-assembling multiprotein complexes.
- understand the concepts of molecular machines and molecular wires, with an emphasis on chemical mechanisms, thermodynamics and electrochemistry.
- recognize the fundamental principles underlying the structure, function and dynamics of biomacromolecules.
Learning outcomes specific to attainment of a pass at Level 11 include:
- ability to integrate all, or most, of the main areas of the course
- development of original and creative responses to problems and issues within the course
- application of critical analysis, evaluation and synthesis to issues at the forefront of the subject area
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Assessment Information
| One 3 hour degree exam. |
Special Arrangements
| None |
Additional Information
| Academic description |
Not entered |
| Syllabus |
Not entered |
| Transferable skills |
Not entered |
| Reading list |
Not entered |
| Study Abroad |
Not entered |
| Study Pattern |
Not entered |
| Keywords | Biom (L11) |
Contacts
| Course organiser | Prof Paul Barlow
Tel: (0131 6)50 4727
Email: Paul.Barlow@ed.ac.uk |
Course secretary | Ms Anne Brown
Tel: (0131 6)50 4754
Email: Anne.Brown@ed.ac.uk |
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