Postgraduate Course: Commercial Aspects of Drug Discovery (PGBI11049)
Course Outline
| School | School of Biological Sciences |
College | College of Science and Engineering |
| Course type | Standard |
Availability | Available to all students |
| Credit level (Normal year taken) | SCQF Level 11 (Postgraduate) |
Credits | 10 |
| Home subject area | Postgraduate |
Other subject area | None |
| Course website |
None |
Taught in Gaelic? | No |
| Course description | This course gives the student a general, illustrated overview over the different stages in drug design from the industrial perspective. The considerations and practicalities of selecting, initiating and running a drug discovery programme will be covered as well as the key topic of finding a lead compound that exhibits the desired biological activity with the highest possible benefits. This course is clearly distinct from the structure-based drug design compulsory module where the topic of rational drug design is covered in detail. The course includes industrial visits and visits from industrial scientists. |
Entry Requirements (not applicable to Visiting Students)
| Pre-requisites |
It is RECOMMENDED that students have passed
Pharmacology (DENT11002)
|
Co-requisites | |
| Prohibited Combinations | |
Other requirements | None |
| Additional Costs | None |
Information for Visiting Students
| Pre-requisites | None |
| Displayed in Visiting Students Prospectus? | Yes |
Course Delivery Information
|
| Delivery period: 2013/14 Semester 2, Available to all students (SV1)
|
Learn enabled: Yes |
Quota: None |
|
Web Timetable |
Web Timetable |
| Course Start Date |
13/01/2014 |
| Breakdown of Learning and Teaching activities (Further Info) |
Total Hours:
100
(
Lecture Hours 14,
External Visit Hours 14,
Formative Assessment Hours 2,
Summative Assessment Hours 3,
Programme Level Learning and Teaching Hours 2,
Directed Learning and Independent Learning Hours
65 )
|
| Additional Notes |
|
| Breakdown of Assessment Methods (Further Info) |
Written Exam
0 %,
Coursework
100 %,
Practical Exam
0 %
|
| No Exam Information |
Summary of Intended Learning Outcomes
Appreciation of various aspects in the drug discovery process, including industrial considerations and the drug testing process.
- Principles of drug action, general topics in medicinal chemistry
- Industrial considerations for picking a drug area (Existing therapies, commercial aspects, etc)
- Lead compounds
Gene profiling
Natural products
Synthetic products
Screening methods: Assays, Microarrays
Libraries, combinatorial chemistry
Rational design (structure-based drug design, etc)
- Assessing lead compounds
Absorption, distribution, metabolism, excretion and toxicology (ADME/tox)
In vitro and in vivo testing
- Drug delivery
- Clinical trials
- Production and marketing
Drug synthesis
Marketing, social, moral aspects
Patents
|
Assessment Information
| A 'Blog' account of each of the sessions. PLUS an essay covering synthesis of drug commercialisation obtained from the visits and outside reading. |
Special Arrangements
| None |
Additional Information
| Academic description |
Not entered |
| Syllabus |
Not entered |
| Transferable skills |
Not entered |
| Reading list |
Not entered |
| Study Abroad |
Not entered |
| Study Pattern |
Not entered |
| Keywords | CADD |
Contacts
| Course organiser | Prof Malcolm Walkinshaw
Tel: (0131 6)50 3719
Email: M.Walkinshaw@ed.ac.uk |
Course secretary | Miss Vicky Mactaggart
Tel: (0131 6)51 7052
Email: Vicky.Mactaggart@ed.ac.uk |
|
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