THE UNIVERSITY of EDINBURGH

DEGREE REGULATIONS & PROGRAMMES OF STUDY 2013/2014 -
- ARCHIVE as at 1 September 2013 for reference only
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DRPS : Course Catalogue : School of Biomedical Sciences : Neuroscience (Biomedical Sciences)

Undergraduate Course: Mechanisms of Forebrain Development (NEBM10029)

Course Outline
SchoolSchool of Biomedical Sciences CollegeCollege of Medicine and Veterinary Medicine
Course typeStandard AvailabilityNot available to visiting students
Credit level (Normal year taken)SCQF Level 10 (Year 4 Undergraduate) Credits10
Home subject areaNeuroscience (Biomedical Sciences) Other subject areaNone
Course website None Taught in Gaelic?No
Course descriptionThe embryonic forebrain gives rise to several structures including the cerebral cortex which is important for all higher cognitive functions unique to humans. Cortical malformations are thought to cause a number of cognitive diseases including mental retardation, epilepsy, autism and schizophrenia. This course will explore the molecular and cellular mechanisms which underlie the normal and abnormal formation of forebrain structures. It will address how signalling pathways and transcription factors interact to pattern the forebrain, the characteristics of embryonic and adult stem cells and how migration and axon pathfinding defects result in cognitive disorders of the cerebral cortex.

Summary of Intended Learning Outcomes:
Demonstrate knowledge and understanding of:
Determinants controlling forebrain patterning;
The roles of a wide range of different cellular processes (proliferation, differentiation, migration, axon pathfinding) involved in cortical development; How abnormal processes can lead to cognitive disorders

Demonstrate an ability to:
Take a critical approach to different models, concepts and approaches to forebrain development.
Make constructive use of research and theory to design and plan projects in forebrain development.
Take an informed part in debate about issues with current concepts of forebrain development.
Entry Requirements (not applicable to Visiting Students)
Pre-requisites Co-requisites
Prohibited Combinations Other requirements None
Additional Costs None
Course Delivery Information
Delivery period: 2013/14 Semester 1, Not available to visiting students (SS1) Learn enabled:  Yes Quota:  25
Web Timetable Web Timetable
Course Start Date 16/09/2013
Breakdown of Learning and Teaching activities (Further Info) Total Hours: 100 ( Lecture Hours 20, Feedback/Feedforward Hours 2, Programme Level Learning and Teaching Hours 2, Directed Learning and Independent Learning Hours 76 )
Additional Notes
Breakdown of Assessment Methods (Further Info) Written Exam 100 %, Coursework 0 %, Practical Exam 0 %
Exam Information
Exam Diet Paper Name Hours:Minutes
Main Exam Diet S1 (December)2:00
Summary of Intended Learning Outcomes
Demonstrate knowledge and understanding of:
Determinants controlling forebrain patterning;
The roles of a wide range of different cellular processes (proliferation, differentiation, migration, axon pathfinding) involved in cortical development; How abnormal processes can lead to cognitive disorders

Demonstrate an ability to:
Take a critical approach to different models, concepts and approaches to forebrain development.
Make constructive use of research and theory to design and plan projects in forebrain development.
Take an informed part in debate about issues with current concepts of forebrain development.
Assessment Information
100% Degree Examination
Special Arrangements
None
Additional Information
Academic description Not entered
Syllabus Not entered
Transferable skills Not entered
Reading list Not entered
Study Abroad Not entered
Study Pattern Not entered
KeywordsNEUROMechoFBD
Contacts
Course organiserDr Thomas Theil
Tel: (0131 6)50 3721
Email: thomas.theil@ed.ac.uk
Course secretaryMs Caroline Morris
Tel: (0131 6)51 3255
Email: c.d.morris@ed.ac.uk
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