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DEGREE REGULATIONS & PROGRAMMES OF STUDY 2013/2014 -
- ARCHIVE as at 1 September 2013 for reference only
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DRPS : Course Catalogue : School of Biomedical Sciences : Physiology (Biomedical Sciences)

Undergraduate Course: Mechanisms of Developmental Neural Plasticity (PYBM10028)

Course Outline
SchoolSchool of Biomedical Sciences CollegeCollege of Medicine and Veterinary Medicine
Course typeStandard AvailabilityNot available to visiting students
Credit level (Normal year taken)SCQF Level 10 (Year 4 Undergraduate) Credits10
Home subject areaPhysiology (Biomedical Sciences) Other subject areaNone
Course website None Taught in Gaelic?No
Course descriptionThis course will examine the mechanisms of nervous system development with special focus on the role of activity in shaping neural connectivity and physiology. It will examine the major advancements in the field of developmental plasticity since the Nobel Prize winning experiments of Hubel and Wiesel in the 1960s. It will examine how the various types of activity (i.e. spontaneous versus sensory-evoked) shape neural connectivity and physiology, drawing on studies using several sensory systems from a variety of mammalian species. We will examine the physiological basis of experience-dependent plasticity with special focus on the role of long-term potentiation and long-term depression on neural development. It will introduce students to recently evolving theories such as metaplasticity and spike-time dependent plasticity as possible mechanisms underlying synaptic information storage. Finally we will examine the molecular basis of activity-dependent plasticity with special focus on glutamate receptors and their downstream signaling pathways. The course will begin with broad introductory lectures covering the foundations of neural development, both embryonic and postnatal, to provide a firm understanding of the major issues confronting developmental neuroscientists. It will then move to seminar-based teaching where students will be expected to critically-evaluate and present recent papers in this rapidly growing field.
Entry Requirements (not applicable to Visiting Students)
Pre-requisites It is RECOMMENDED that students have passed Curriculum (EDUA11017) AND Neuroscience (LISC11038) AND The Curriculum (MEED11014) AND Physiology 3 (BIME09004)
Co-requisites
Prohibited Combinations Other requirements None
Additional Costs Photocopying papers and overheads
Course Delivery Information
Delivery period: 2013/14 Semester 1, Not available to visiting students (SS1) Learn enabled:  Yes Quota:  None
Web Timetable Web Timetable
Course Start Date 16/09/2013
Breakdown of Learning and Teaching activities (Further Info) Total Hours: 100 ( Lecture Hours 10, Seminar/Tutorial Hours 10, Summative Assessment Hours 2, Programme Level Learning and Teaching Hours 2, Directed Learning and Independent Learning Hours 76 )
Additional Notes
Breakdown of Assessment Methods (Further Info) Written Exam 100 %, Coursework 0 %, Practical Exam 0 %
Exam Information
Exam Diet Paper Name Hours:Minutes
Main Exam Diet S1 (December)Mechanisms of Developmental Neural Plasticity1:30
Summary of Intended Learning Outcomes
Increased understanding of biological processes.
Detailed learning outcomes will be provided later.
Assessment Information
December exam. Written exam 100%. Duration 1 hour 15 minutes.
Special Arrangements
None
Additional Information
Academic description Not entered
Syllabus Not entered
Transferable skills Not entered
Reading list Not entered
Study Abroad Not entered
Study Pattern Not entered
KeywordsPHYSMechdevneural
Contacts
Course organiserDr Mike Ludwig
Tel: (0131 6)50 3275
Email: Mike.Ludwig@ed.ac.uk
Course secretaryMrs Patricia Law
Tel: (0131 6)50 3161
Email: Anne.Law@ed.ac.uk
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