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DEGREE REGULATIONS & PROGRAMMES OF STUDY 2014/2015
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DRPS : Course Catalogue : School of Chemistry : Chemistry

Undergraduate Course: Biomacromolecules Level 10 (CHEM10051)

Course Outline
SchoolSchool of Chemistry CollegeCollege of Science and Engineering
Credit level (Normal year taken)SCQF Level 10 (Year 4 Undergraduate) AvailabilityAvailable to all students
SCQF Credits20 ECTS Credits10
SummaryA course of lectures and a workshop covering synthesis, chemistry, structure, function and engineering of biological polymers. The course will teach how biopolymers are constructed from simple building blocks, and folded into three-dimensional structures. The ability of biomacromolecules to dynamically and specifically interact and cooperate with one another, on a range of timescales and affinities, will be discussed. The course will also cover production of modified or engineered biomacromolecules. Chemical complexity and functional capabilities arising from prosthetic groups, cofactors, metal ions and post-translational modifications will be described as will the ability of proteins to act as molecular wires and biological catalysts. The taught material will include components on protein manufacture and validation, protein and nucleic acid chemistry, enzymology, metalloproteins, and the role of proteins in cellular electrochemistry.

Either the Level 10 or Level 11 version of this course version of this course (as specified in the degree programme tables) is a compulsory requirement for Year 4/5 students on degrees in Medicinal and Biological Chemistry, but can be taken by Year 4/5 students on any Chemistry degree programme.
Course description Not entered
Entry Requirements (not applicable to Visiting Students)
Pre-requisites Students MUST have passed: Chemistry 3A (CHEM09005) AND Chemistry 3B (CHEM09006) AND Chemistry 3P Practical and Transferable Skills (CHEM09007)
Co-requisites
Prohibited Combinations Students MUST NOT also be taking Biomacromolecules Level 11 (CHEM11043)
Other requirements Must include a weighted average of Grade D or higher in Chemistry 3A and Chemistry 3B, at the first attempt; or with the permission of Head of School.
Information for Visiting Students
Pre-requisitesNone
Course Delivery Information
Academic year 2014/15, Available to all students (SV1) Quota:  None
Course Start Semester 1
Timetable Timetable
Learning and Teaching activities (Further Info) Total Hours: 200 ( Lecture Hours 24, Seminar/Tutorial Hours 9, Supervised Practical/Workshop/Studio Hours 6, Summative Assessment Hours 2.5, Revision Session Hours 6, Programme Level Learning and Teaching Hours 4, Directed Learning and Independent Learning Hours 149 )
Assessment (Further Info) Written Exam 100 %, Coursework 0 %, Practical Exam 0 %
Additional Information (Assessment) One 2.5 hour exam.
Feedback Not entered
Exam Information
Exam Diet Paper Name Hours & Minutes
Main Exam Diet S2 (April/May)2:30
Academic year 2014/15, Part-year visiting students only (VV1) Quota:  None
Course Start Semester 1
Timetable Timetable
Learning and Teaching activities (Further Info) Total Hours: 200 ( Lecture Hours 24, Seminar/Tutorial Hours 9, Supervised Practical/Workshop/Studio Hours 6, Summative Assessment Hours 2.5, Revision Session Hours 6, Programme Level Learning and Teaching Hours 4, Directed Learning and Independent Learning Hours 149 )
Assessment (Further Info) Written Exam 100 %, Coursework 0 %, Practical Exam 0 %
Additional Information (Assessment) One 2.5 hour exam.
Feedback Not entered
Exam Information
Exam Diet Paper Name Hours & Minutes
Main Exam Diet S1 (December)2:30
Learning Outcomes
On completion of this course, the student will be able to:
  1. Upon completion of this course students should be able to:
    - explain the biosynthesis as well as the laboratory-based manufacture and purification of biologically important polymers.
    - appreciate how knowledge of macromolecular 3D structure illuminates the understanding of mechanism and how (with examples) "form follows function".
    - understand, through the study of examples, the principles of molecular recognition and cooperation, molecular crowding and self-assembling multiprotein complexes.
    - understand the concepts of molecular machines and molecular wires, with an emphasis on chemical mechanisms, thermodynamics and electrochemistry.
    - recognize the fundamental principles underlying the structure, function and dynamics of biomacromolecules.
Reading List
None
Additional Information
Graduate Attributes and Skills Not entered
KeywordsBiom (L10)
Contacts
Course organiserProf Paul Barlow
Tel: (0131 6)50 4727
Email: Paul.Barlow@ed.ac.uk
Course secretaryMs Anne Brown
Tel: (0131 6)50 4754
Email: Anne.Brown@ed.ac.uk
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