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DRPS : Course Catalogue : School of Biomedical Sciences : Microbiology and Infection (Biomedical Sciences)

Undergraduate Course: Host-pathogen interactions in Infectious Disease (MIBM10052)

Course Outline
SchoolSchool of Biomedical Sciences CollegeCollege of Medicine and Veterinary Medicine
Credit level (Normal year taken)SCQF Level 10 (Year 4 Undergraduate) AvailabilityNot available to visiting students
SCQF Credits20 ECTS Credits10
SummaryLectures: This course focuses on fundamental aspects of pathogen-host interactions and covers the biological mechanisms and processes which lead to pathogenesis and disease following infection. There is an emphasis on the application of modern research methods and approaches in this field. This course comprises three main themes:
Experimental approaches to study Microbial pathogenesis:
Identification of virulence factors
Animal models
Genome wide approaches to study host-pathogen interactions
Monitoring host response and immunity to pathogens
Pathobiology of Infection:
Survival strategies of bacterial, viral and parasite pathogens.
Modulation of the host immune response
Mechanisms of pathogenesis
Manipulation and reprogramming of the intracellular environment
Infection of the human host Gastrointestinal Infections, Respiratory infections, CNS infections, Neonatal infection
Pathogen ecology and evolution:
Evolution of bacterial virulence
Molecular evolution of viruses and other pathogens

Tutorials: A series of tutorials will cover essay, abstract and report writing, scientific techniques, presentation skills, scientific calculations and statistics, and the critical analysis of scientific papers. The tutorials will provide important formative feedback/forward for assignments and activities in the course as a whole.
Course description Not entered
Entry Requirements (not applicable to Visiting Students)
Pre-requisites Co-requisites
Prohibited Combinations Other requirements None
Course Delivery Information
Academic year 2014/15, Not available to visiting students (SS1) Quota:  None
Course Start Full Year
Timetable Timetable
Learning and Teaching activities (Further Info) Total Hours: 200 ( Lecture Hours 30, Seminar/Tutorial Hours 10, Formative Assessment Hours 4, Summative Assessment Hours 4, Programme Level Learning and Teaching Hours 4, Directed Learning and Independent Learning Hours 148 )
Assessment (Further Info) Written Exam 35 %, Coursework 65 %, Practical Exam 0 %
Additional Information (Assessment) 15% ICA Semester 1: 1500 word essay
50% ICA Semester 2: Scientific literature Interpretation test a series of comprehension questions on a scientific paper. The paper will have the title and abstract removed. The students will also be required to write a suitable abstract and title.
35% Exam
Feedback Not entered
Exam Information
Exam Diet Paper Name Hours & Minutes
Main Exam Diet S2 (April/May)2:00
Learning Outcomes
On completion of this course, the student will be able to:
  1. Explain and critically assess experimental approaches to study Microbial pathogenesis
  2. Explain the survival strategies of bacterial, viral or parasitic pathogens in the host
  3. Explain the host immune response to pathogens and how pathogens can overcome this
  4. Identify the different host systems affected by pathogens
  5. Recognise the importance of the evolution of pathogens and virulence

    Critical analysis of scientific literature through the study of key papers
Reading List
None
Additional Information
Graduate Attributes and Skills Not entered
KeywordsBacteria, Virus, Parasite, Pathogenesis, Pathogen, Immune system, host-pathogen interactions
Contacts
Course organiserDr Douglas Roy
Tel: (0131) 242 6279
Email: Douglas.Roy@ed.ac.uk
Course secretaryMs Tracy Noden
Tel: (0131 6)50 3717
Email: Tracy.Noden@ed.ac.uk
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