Undergraduate Course: Neural Regulatory Mechanisms (PHBM10032)
Course Outline
| School | School of Biomedical Sciences |
College | College of Medicine and Veterinary Medicine |
| Credit level (Normal year taken) | SCQF Level 10 (Year 4 Undergraduate) |
Availability | Not available to visiting students |
| SCQF Credits | 10 |
ECTS Credits | 5 |
| Summary | This course will address fundamental principles of regulatory mechanisms within neurons and between glia and neurons that may pinpoint new molecular targets for intervention in diverse pathological conditions. We will explore the roles of key receptors and other cell surface proteins, their protein:protein interactions and downstream signalling pathways, in synaptic and other forms of plasticity at different sites in the nervous system. We will further consider how these can be investigated by a multidisciplinary range of techniques. The aim of this course is not only to deliver specific information at the cutting edge of research but also to emphasise how elucidation of molecular mechanisms may provide the long term promise of novel treatment strategies to fulfil currently unmet therapeutic needs. The programme will include a series of research-oriented lectures by experts in their fields.
These will include: the role of interacting proteins in glial/neuronal communication and assembly of receptor signalling complexes in relation to pain and motor disorders, the role of growth factor receptors and their individual signalling pathways in neurological disorders and the potential therapeutic opportunities offered by targeting protein interfaces or by allosteric and pathway-selective receptor ligands.
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| Course description |
Not entered
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Entry Requirements (not applicable to Visiting Students)
| Pre-requisites |
It is RECOMMENDED that students have passed
Pharmacology 3 (BIME09003)
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Co-requisites | |
| Prohibited Combinations | |
Other requirements | None |
| Additional Costs | None |
Course Delivery Information
| Not being delivered |
Learning Outcomes
Demonstrate knowledge and understanding of:
-Molecular regulatory mechanisms in neurons and glia and how their dysfunction may lead to diverse pathological conditions.
-Ways in which elucidating molecular mechanisms can potentially provide avenues for the development of novel therapeutics.
Demonstrate an ability to:
-Bring together information from multidisciplinary sources and experimental approaches to develop a reasoned understanding of mechanisms.
-Critically analyse original research papers, evaluating the benefits and limitations of particular approaches and what can be interpreted from them.
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Additional Information
| Graduate Attributes and Skills |
Not entered |
| Keywords | NRM |
Contacts
| Course organiser | Dr David Wyllie
Tel: (0131 6)50 4564
Email: David.J.A.Wyllie@ed.ac.uk |
Course secretary | Mr Neale Summers
Tel: (0131 6)51 3094
Email: n.summers@ed.ac.uk |
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