Postgraduate Course: Drug Discovery (MSc Level) (PGBI11088)
Course Outline
| School | School of Biological Sciences |
College | College of Science and Engineering |
| Course type | Standard |
Availability | Not available to visiting students |
| Credit level (Normal year taken) | SCQF Level 11 (Postgraduate) |
Credits | 10 |
| Home subject area | Postgraduate |
Other subject area | None |
| Course website |
None |
Taught in Gaelic? | No |
| Course description | This course provides a broad overview of the drug discovery and development process, and in particular structure based drug design. Pharmaceutical drugs have traditionally developed from herbal remedies or from the random screening for beneficial effects of natural or synthetic chemicals. We now have a detailed understanding of many diseases at a molecular level.
The aim of this course is to explain how we can use the structure and function of proteins involved in a disease to discover new potential drug molecules. The course provides a background on how proteins are selected as potential disease targets and introduces the various biochemical, computational and biophysical techniques used in ligand discovery.
The course also has a practical component and computational workshops will provide hands-on experience with modeling and docking programs to identify potential small molecule ligands as potential inhibitors against a number of protein drug targets. |
Entry Requirements (not applicable to Visiting Students)
| Pre-requisites |
|
Co-requisites | |
| Prohibited Combinations | |
Other requirements | None |
| Additional Costs | None |
Course Delivery Information
|
| Delivery period: 2014/15 Block 3 (Sem 2), Not available to visiting students (SS1)
|
Learn enabled: Yes |
Quota: 24 |
|
Web Timetable |
Web Timetable |
| Class Delivery Information |
Classes taken alongside Honours course 'Drug Discovery' BICH10016 |
| Course Start Date |
12/01/2015 |
| Breakdown of Learning and Teaching activities (Further Info) |
Total Hours:
100
(
Lecture Hours 20,
Programme Level Learning and Teaching Hours 2,
Directed Learning and Independent Learning Hours
78 )
|
| Additional Notes |
|
| Breakdown of Assessment Methods (Further Info) |
Written Exam
0 %,
Coursework
100 %,
Practical Exam
0 %
|
| No Exam Information |
Summary of Intended Learning Outcomes
After completing this course, students should have:
¿ Increased understanding of biological and biochemical systems.
¿ An overview of the methods used in structure-based drug design
¿ An appreciation of the role molecular structure and biochemical mechanisms play in the design of new drug modules
¿ Improved presentation skills
¿ Used molecular modelling software to visualise drug-target complexes |
Assessment Information
Power Point presentation handout (20%)
Group presentation of 2 pages (12 slides in total) summarising the project and evaluating the target.
Written Report (80%)
Each student will write an individual report as if for a pharmaceutical company who are evaluating your protein as a therapeutic target. |
Special Arrangements
| None |
Additional Information
| Academic description |
Not entered |
| Syllabus |
Not entered |
| Transferable skills |
Not entered |
| Reading list |
Not entered |
| Study Abroad |
Not entered |
| Study Pattern |
Not entered |
| Keywords | DrugDisc |
Contacts
| Course organiser | Prof Malcolm Walkinshaw
Tel: (0131 6)50 3719
Email: M.Walkinshaw@ed.ac.uk |
Course secretary | Miss Vicky Mactaggart
Tel: (0131 6)51 7052
Email: Vicky.Mactaggart@ed.ac.uk |
|
© Copyright 2014 The University of Edinburgh - 29 August 2014 4:27 am
|
University Homepage