THE UNIVERSITY of EDINBURGH

DEGREE REGULATIONS & PROGRAMMES OF STUDY 2014/2015
- ARCHIVE as at 1 September 2014

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DRPS : Course Catalogue : School of Biomedical Sciences : Pharmacology (Biomedical Sciences)

Undergraduate Course: Drugs, Receptors and Therapeutics (PHBM10036)

Course Outline
SchoolSchool of Biomedical Sciences CollegeCollege of Medicine and Veterinary Medicine
Course typeStandard AvailabilityNot available to visiting students
Credit level (Normal year taken)SCQF Level 10 (Year 4 Undergraduate) Credits20
Home subject areaPharmacology (Biomedical Sciences) Other subject areaNone
Course website None Taught in Gaelic?No
Course descriptionAn understanding of the molecular pharmacology of receptors in relation to the action of drugs underpins many aspects of the courses within Honours Pharmacology Programmes. A series of lectures will be given to provide an overview of topics, including: action of drugs at receptors, structure-function relationships for the different classes of receptor, the signalling processes following receptor activation and receptor cloning and expression. The course will also provide a coherent perspective of how drugs are developed from a molecular target through preclinical development to clinical trials. It will consider how academic pharmacology can interact with drug development or can be focussed on discovery of molecular mechanisms independent of immediate therapeutic potentials. The economic drivers and processes (project proposal, grant funding and hypothesis formulation) in the industrial and academic domains will be considered. There will be opportunity to meet with Programme tutors in small groups. The purpose of the tutorials is to provide student access to a member of staff and to cover general aspects related to Pharmacology. Students will be encouraged to submit essays to tutors in order to practice and obtain feedback on their writing skills.
Entry Requirements (not applicable to Visiting Students)
Pre-requisites Co-requisites
Prohibited Combinations Other requirements None
Additional Costs None
Course Delivery Information
Delivery period: 2014/15 Full Year, Not available to visiting students (SS1) Learn enabled:  Yes Quota:  None
Web Timetable Web Timetable
Course Start Date 15/09/2014
Breakdown of Learning and Teaching activities (Further Info) Please contact the School directly for a breakdown of Learning and Teaching Activities
Additional Notes
Breakdown of Assessment Methods (Further Info) Written Exam 70 %, Coursework 30 %, Practical Exam 0 %
No Exam Information
Summary of Intended Learning Outcomes
Demonstrate knowledge and understanding of;
- the major classes of receptors and their potential for therapeutic targeting
- the principles of ligand-receptor interactions together with an ability to understand simple kinetic schemes describing receptor activation
- downstream mechanisms of intracellular signalling
- the drug discovery process and the stages involved from target identification to commercial release of a new therapeutic

Demonstrate an ability to:
-discuss and critically evaluate the different experimental and quantitative methodologies that have expanded our knowledge of pharmacology and pharmacological action of drugs,
- interpret and evaluate information in original articles and figures,
- draw together information from different approaches to identify the underlying mechanisms that might contribute the development of new therapeutics to treat disease
Assessment Information
30% In-Course Assessment
70% Written Exam
Special Arrangements
None
Additional Information
Academic description Not entered
Syllabus Not entered
Transferable skills Not entered
Reading list Not entered
Study Abroad Not entered
Study Pattern Not entered
KeywordsPharmacology, drugs, receptors, receptor theory, cloning, structure activity relationships, signalli
Contacts
Course organiserProf Anthony Evans
Tel: (0131 6)51 1501
Email: mark.evans@ed.ac.uk
Course secretaryMr Neale Summers
Tel: (0131 6)51 3094
Email: n.summers@ed.ac.uk
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