Postgraduate Course: High Throughput Drug Discovery (PGBI11077)
|School||School of Biological Sciences
||College||College of Science and Engineering
|Credit level (Normal year taken)||SCQF Level 11 (Postgraduate)
||Availability||Not available to visiting students
|Summary||**Online Distance Learning Course**
The focus of high throughput screening in drug discovery has been on automating assay techniques so that large libraries of molecules could be screened against disease relevant targets. Over time, this has developed to include a wide array of assay and screening technologies to provide a broad range of parameters and physiologically relevant information. The ultimate aim in this area is to reduce the screening costs per compound allowing routine screening of large libraries in an assay method appropriate to the drug target.
Entry Requirements (not applicable to Visiting Students)
||Other requirements|| None
Course Delivery Information
|Academic year 2016/17, Not available to visiting students (SS1)
|Course Start Date
|Learning and Teaching activities (Further Info)
Online Activities 20,
Programme Level Learning and Teaching Hours 2,
Directed Learning and Independent Learning Hours
|Assessment (Further Info)
|Additional Information (Assessment)
||50 % group assessment (including maximum 20% variation for Peer Assessment of contribution)
50 % electronic portfolio comprising learning log and contribution to Skills Profile
|No Exam Information
On completion of this course, the student will be able to:
- Understand the basics of assay design for use in large scale multiwell robotic screening environments
- Be aware of the issues of reproducibility and false positive/negative signal generation in these types of assay platforms.
- Describe the principles of combinatorial chemistry as applied to the drug discovery process.
- Show an understanding of the various screening techniques and assay methods currently used in drug discovery
- Analyse high throughput screening data and calculate the Z¿ value to indicate assay quality.
|Graduate Attributes and Skills
|Course organiser||Prof Manfred Auer
|Course secretary||Mrs Claire Black
Tel: (0131 6)50 8637
© Copyright 2016 The University of Edinburgh - 3 February 2017 4:51 am