Undergraduate Course: Scientific Frontiers of Medicine (BIME10055)
|School||Deanery of Biomedical Sciences
||College||College of Medicine and Veterinary Medicine
|Credit level (Normal year taken)||SCQF Level 10 (Year 4 Undergraduate)
||Availability||Not available to visiting students
|Summary||This course will provide a comprehensive overview of fundamental knowledge and concepts that are central to the advancement of modern medical research. A translational bench-to-bedside approach will be adopted and biomedical and clinical research in diseases that affect diverse organs will be examined. Experimental systems used to mechanistically dissect human disease and their cellular and molecular analysis will be examined. Examples of topics covered include the role of fundamental biological processes (inflammation, fibrosis) in human disease pathogenesis, mechanisms of tissue healing, regenerative medicine including the use of stem cells, novel biomarkers of human disease (e.g. microRNA, proteins, extracellular vesicles) and the impact of genetics and aging upon disease processes. Methods to study of human disease will cover genetic analyses, translational imaging modalities and novel technologies. This course will provide a coherent and holistic perspective of multiple areas of modern cutting edge research in diverse human disease and their contribution to current and future medicine.
This course will provide a comprehensive overview of fundamental knowledge and concepts that are central to the advancement of modern medical research including personalised precision medicine and patient stratification. The course will examine experimental systems used to mechanistically dissect human disease and their cellular and molecular analysis from a bench-to-bedside perspective. The role of fundamental pathophysiological processes such as ischaemia, aberrant immune response, inflammation and fibrotic scarring in diseases affecting multiple organs such as the heart, liver, lung and kidney will be explored. Other areas that will be examined include tissue healing and regenerative medicine including stem cells, novel biomarkers of human disease (e.g. microRNA, proteins, extracellular vesicles) and the impact of genetics and aging upon disease. Methods to study of human disease will cover the use of clinical trials, genetic analyses, translational imaging modalities and novel technologies such as proteomics. The process of modern drug development including the use of high throughput screening assays will be examined. This course will provide a coherent and holistic perspective of the multiple areas of research and their contribution to current and future medicine.
The Scientific Frontiers in Medicine course will provide students with a broad appreciation of the range of modern medical research across a broad range of specialities. In addition, cutting edge research findings will be presented to demonstrate the approaches, methods and technology being used to address research questions by academic clinicians. The programme will use lectures and tutorials and offer opportunity for discussion.
Entry Requirements (not applicable to Visiting Students)
||Other requirements|| None
Course Delivery Information
|Academic year 2018/19, Not available to visiting students (SS1)
|Learning and Teaching activities (Further Info)
Lecture Hours 45,
Programme Level Learning and Teaching Hours 4,
Directed Learning and Independent Learning Hours
|Assessment (Further Info)
|Additional Information (Assessment)
A 2-hour written exam in December diet (70%)
Preparation and communication of a Poster (week 6, Semester 1) covering a medical topic chosen from a list provided to students (30%)
||The poster will be assessed during the poster presentation session and direct feedback provided to the student.
A structured questionnaire will be used to gather student feedback on the components of the course.
||Hours & Minutes
|Main Exam Diet S1 (December)||2:00|
On completion of this course, the student will be able to:
- Demonstrate a critical understanding of the principles of modern medical research.
- Discuss and critically evaluate the different experimental and quantitative methodologies used to research and expand our knowledge of medicine including the role of experimental models of human disease.
- Demonstrate knowledge and understanding of how multiple biological factors (e.g. immune responses, genetics and aging) impact upon the development and progression of disease within individuals.
- Critically evaluate information from different approaches (e.g. studies of experimental models, genetic analyses of patient cohorts) to identify the underlying mechanisms that might contribute to disease pathogenesis, diagnosis or the efficacy of treatment strategies.
- Demonstrate knowledge and understanding of the use of cutting edge biomedical science (e.g. proteomics, imaging, stem cells) to drive advances in medical research. Make effective use of information and communications technology to critically appraise relevant information from the medical research literature and present information to others.
Original relevant research journal articles
|Graduate Attributes and Skills
||Students will have a broad overview of modern medical research and gain an understanding of important research issues and how they are dissected. Students will be able to evaluate and critically appraise biomedical and clinical research papers. Students will gain information and communication technology skills, manage their time effectively and work as part of a team in a professional manner.
|Course organiser||Dr Richard Weller
Tel: (0131) 536 3229
|Course secretary||Miss Morag Wilson
Tel: (0131 6) 509 414