Postgraduate Course: Introduction to Modelling Biological Systems (PGBI11072)
Course Outline
| School | School of Biological Sciences |
College | College of Science and Engineering |
| Credit level (Normal year taken) | SCQF Level 11 (Postgraduate) |
| Course type | Online Distance Learning |
Availability | Not available to visiting students |
| SCQF Credits | 10 |
ECTS Credits | 5 |
| Summary | **Online Learning Course**
This course will address the problem that drugs designed against a specific target don't always work as they were intended. In particular, when a drug target is part of a pathway, its inhibition often isn't as effective as was predicted from the properties of the protein in isolation. This course will introduce kinetic modelling of a system of enzymes in which the system has emergent properties that were not obvious from the behaviour of the individual components. The effects of putative inhibitors to one or more of these will be investigated by creating computer models. |
| Course description |
Not entered
|
Entry Requirements (not applicable to Visiting Students)
| Pre-requisites |
|
Co-requisites | |
| Prohibited Combinations | |
Other requirements | None |
Course Delivery Information
|
| Academic year 2019/20, Not available to visiting students (SS1)
|
Quota: None |
| Course Start |
Flexible |
| Course Start Date |
05/08/2019 |
Timetable |
Timetable |
| Learning and Teaching activities (Further Info) |
Total Hours:
100
(
Online Activities 20,
Programme Level Learning and Teaching Hours 2,
Directed Learning and Independent Learning Hours
78 )
|
| Assessment (Further Info) |
Written Exam
0 %,
Coursework
100 %,
Practical Exam
0 %
|
| Additional Information (Assessment) |
25% = Individual Wiki
15% = Group discussion tasks
10% = Jing talk
50% = Electronic Portfolio (comprising of learning log and contribution to skills profile)
|
| Feedback |
Not entered |
| No Exam Information |
Learning Outcomes
On completion of this course, the student will be able to:
- Derive kinetic parameters from the scientific literature and databases
- Model the time evolution of substrates and products for an individual enzyme
- Make more sophisticated models by including more elements
- Investigate emergent properties of a system of enzymes
- Appreciate how model properties may be verified experimentally
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Additional Information
| Graduate Attributes and Skills |
Not entered |
| Keywords | IntroMBS |
Contacts
| Course organiser | Dr Paul Michels
Tel:
Email: Paul.Michels@ed.ac.uk |
Course secretary | Mrs Claire Black
Tel: (0131 6)50 8637
Email: Claire.Black@ed.ac.uk |
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