Undergraduate Course: Immunobiology of Malaria (IMMU10007)
|School||School of Biological Sciences
||College||College of Science and Engineering
|Credit level (Normal year taken)||SCQF Level 10 (Year 4 Undergraduate)
||Availability||Not available to visiting students
|Summary||This course is designed to provide an advanced understanding of practical and theoretical consequences of immunological processes triggered by malaria, a leading cause of morbidity and mortality in the tropics. Immune responses can benefit or harm the host, and the course will examine immune mechanisms that can mediate protection as well as pathways responsible for malaria pathology. Topics of lectures and/or discussion sessions will include: An overview of Plasmodia, their biology & the role of sexual reproduction in the generation of antigenic diversity. Animal models of malaria immunity and of pathogenesis. Pathogenesis of human malaria, a spectrum of clinical forms. The dynamics & hypotheses of acquired immunity in humans. Parasite modulation of host responses, immunodepression & interactions with other infections. P. falciparum genome & antigen genes. Development of malaria vaccines. Population genetics & some evolutionary aspects of vaccine deployment
This elective aims to provide an advanced immunological understanding of malaria, arguable the most important parasitic infection of mankind and an outstanding challenge to practical immunology. The emphasis will be on human malaria, though animal models will be considered when appropriate to current hypotheses of immunity and/or pathogenesis.
Course Delivery Information
|Academic year 2020/21, Not available to visiting students (SS1)
|Learning and Teaching activities (Further Info)
Lecture Hours 27,
Summative Assessment Hours 2,
Revision Session Hours 3,
Programme Level Learning and Teaching Hours 2,
Directed Learning and Independent Learning Hours
|Assessment (Further Info)
|Additional Information (Assessment)
||Longitudinal assessment: Assessed by Essay and Abstract submission.
|No Exam Information
On completion of this course, the student will be able to:
- Advanced understanding of the immunological processes triggered by infection with malaria parasites.
- Attainment of advanced skills in reading, understanding and evaluating primary scientific papers.
- Development of oral presentation skills and written communication skills.
|Graduate Attributes and Skills
|Course organiser||Prof Alex Rowe
Tel: (0131 6)50 5492
|Course secretary||Mr Tim MacDonald
Tel: (0131 6)51 7296