Postgraduate Course: Advanced Analytical Chemistry PGT (CHEM11083)
|School||School of Chemistry
||College||College of Science and Engineering
|Credit level (Normal year taken)||SCQF Level 11 (Postgraduate)
||Availability||Not available to visiting students
|Summary||This course will provide advanced teaching in a range of analytical and measurement techniques.
The physical basis for each technique will be discussed in detail. Theoretical knowledge will be supported by a selection of case studies to emphasise the applications of these techniques to solve complex analytical problems. The course forms a part of the curriculum for any student enrolled on the PGT MSc degree course in Analytical Chemistry.
The course consists of 30 lectures divided into five lecture modules. The content of these courses builds on the fundamental knowledge delivered in Foundations of Analytical Chemistry. Each lecture module describes advanced theory and applications of a single analytical technique or group of related techniques. Emphasis is given on the applications of these techniques in the modern analytical chemistry laboratory. The strengths and limitations of each will be discussed and the requirement for the application of a range of complementary techniques to answer complex analytical challenges will be highlighted. The following topics are included in this course:
· Optical spectroscopic techniques. Including fluorescence techniques such as FRET, fluorescence lifetime and single molecule; vibrational techniques such as Raman spectroscopy (SERS, SORS, SERRS, TERS).
· Chromatography techniques. An in depth look at chromatographic theory. GC, HPLC and UPLC methods. Chromatography method development and problem solving.
· Mass spectrometry, Isotope Ratio Mass Spectrometry, and related gas phase techniques such as ion mobility spectroscopy. An in depth look at high resolution MS analysers. The application of mass spectrometry to proteomics and metabolomics.
· NMR spectroscopy (including homonuclear and heteronuclear multidimensional NMR techniques, DOSY techniques, quantitative NMR (qNMR), and reaction monitoring by NMR).
Each lecture module is followed by a tutorial class session where problems arising from the content can be discussed.
Entry Requirements (not applicable to Visiting Students)
||Other requirements|| None
Course Delivery Information
|Academic year 2022/23, Not available to visiting students (SS1)
|Learning and Teaching activities (Further Info)
Lecture Hours 30,
Seminar/Tutorial Hours 7.5,
Feedback/Feedforward Hours 5,
Summative Assessment Hours 12,
Revision Session Hours 5,
Programme Level Learning and Teaching Hours 4,
Directed Learning and Independent Learning Hours
|Assessment (Further Info)
|Additional Information (Assessment)
||Exam (75%) and Coursework (25%)
||Each lecture module has an associated tutorial. This will provide students with practice at problem-solving and tackling coursework-like questions. It is also an opportunity for students to discuss any issues pertaining to the lecture course.
||Hours & Minutes
|Main Exam Diet S2 (April/May)||Advanced Analytical Chemistry||3:00|
On completion of this course, the student will be able to:
- Show an understanding of the theory and application of several techniques in analytical chemistry.
- Apply this knowledge to select and justify appropriate techniques for chemical analyses, molecular measurements or data analyses.
- Develop responses to problems and issues in aspects of analytical chemistry and data analysis.
- Apply a set of numerical skills for solving quantitative analytical chemistry and data analysis problems.
- Demonstrate a professional approach to autonomy and time-management in relation to self-study.
|To be provided by individual course lecturers.|
|Graduate Attributes and Skills
||1. Note-taking skills
2. Numerical data interpretation and analysis
3. Unseen problem solving skills
|Course organiser||Dr David Clarke
Tel: (0131 6)50 4808
|Course secretary||Ms Zoe Burger
Tel: (0131 6)50 7546