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DRPS : Course Catalogue : Royal (Dick) School of Veterinary Studies : Veterinary Sciences

Postgraduate Course: Introduction to Models of Disease - Bioscience and Ethics (VESC11244)

Course Outline
SchoolRoyal (Dick) School of Veterinary Studies CollegeCollege of Medicine and Veterinary Medicine
Credit level (Normal year taken)SCQF Level 11 (Postgraduate) AvailabilityNot available to visiting students
SCQF Credits20 ECTS Credits10
SummaryIn this course all students will receive a wide-ranging lecture-based teaching covering the major themes of the Programme: Modelling disease; Genome modification; Tissue and cell-based models; Large animal models; and Imaging techniques for one health models of disease.
Course description Teaching will give in depth understanding of both the bioscience of these topics and its ethical and social implications. Lectures topics will include novel animal models of human disorders generated via genome editing, surgery, gene therapy or transgenesis; development and pre-clinical evaluation of novel therapies and diagnostics; 3Rs approaches to study of disease; understanding gene function in the context of infection or disease via genome-scale mutagenesis; and comparative biology of diseases shared by humans and animals (e.g. tuberculosis, influenza, enteric pathogens). These lectures will highlight the role that one health models of disease have played in advancing knowledge. In alternating week there will be facilitated discussions with members of the Centre for Biomedicine, Self and Society about the ethical issues raised by the bioscience research showcased in the portrait lectures.

Teaching will be delivered in small groups with considerable time allowed for discussion and in-depth exploration of the issues raised.
Entry Requirements (not applicable to Visiting Students)
Pre-requisites Co-requisites
Prohibited Combinations Other requirements None
Course Delivery Information
Academic year 2023/24, Not available to visiting students (SS1) Quota:  None
Course Start Full Year
Timetable Timetable
Learning and Teaching activities (Further Info) Total Hours: 200 ( Seminar/Tutorial Hours 50, Feedback/Feedforward Hours 1, Summative Assessment Hours 1, Programme Level Learning and Teaching Hours 4, Directed Learning and Independent Learning Hours 144 )
Assessment (Further Info) Written Exam 0 %, Coursework 100 %, Practical Exam 0 %
Additional Information (Assessment) 100% coursework

75% - 2000 word essay discussing contribution of One Health Model to understanding disease in a body system of the student's choice

25% - Oral presentation on relevant ethical issue in development and use of One Health models.
Feedback Students will be given written feedback on their essay and oral presentation.
No Exam Information
Learning Outcomes
On completion of this course, the student will be able to:
  1. demonstrate knowledge of One Health approaches can be used to generate models applicable to human and animals disease
  2. appreciate the technological basis for genome modification and gene editing, and the ethical implications of these techniques
  3. understand how large animal, tissue cell-based models are used to study disease in humans and animals
  4. recognise how bioimaging techniques are used to study One Health models of disease
  5. appreciate the 3Rs - Replacement, Reduction and Refinement - approach to use of animals in research
Reading List
Additional Information
Graduate Attributes and Skills Upon completion of this course students will have developed a wide range of Graduate Attributes and Skills that will contribute to their professional growth as successful researchers and experts in their field.

Through exposure to world-leading research, they are innovative and lifelong learners.
By taking a confident and reflective approach to their learning, they take personal responsibility for pushing their goals and opportunities to grow.
KeywordsModelling disease,Genome modification,Tissue and cell-based models,Large animal models,Imaging
Course organiserProf Jonathan Fitzgerald
Tel: (0131 6)51 9235
Course secretaryMiss Jennifer Hurst
Tel: (0131 6)51 3685
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