Undergraduate Course: Biological Chemistry 2 (CHEM08030)

Course Outline
School	School of Chemistry	College	College of Science and Engineering
Credit level (Normal year taken)	SCQF Level 8 (Year 2 Undergraduate)	Availability	Available to all students
SCQF Credits	20	ECTS Credits	10
Summary	A lecture course providing instruction in aspects of biological chemistry. A sound knowledge of chemistry is essential for understanding the structures, reactivities and interactions of biomolecules. The course comprises individual lecture series including biomolecular structure and chemistry, biosynthesis of natural products, biological inorganic chemistry, analytical techniques in biochem, and fundamentals of medicinal chemistry.
Course description	The course consists of 30 lectures divided into five lecture modules outlined above. Each lecture module is geared to presenting the important basic principles (at a second year level) illustrating the relevance of these using typical examples. Each module course is followed by a tutorial/examples class session where problems arising from the content can be discussed. The laboratory course consists of four experiments which are designed to improve hands-on practical and analytical skills.

Entry Requirements (not applicable to Visiting Students)
Pre-requisites	Students MUST have passed: Biological Chemistry 1B (CHEM08023) OR Chemistry 1A (CHEM08016) AND Chemistry 1B (CHEM08017)	Co-requisites
Prohibited Combinations		Other requirements	This course is suitable for students who have studied at first year undergraduate chemistry level. Students who have been granted direct entry into second year of a Chemistry degree programme may also enrol in this course. Direct entry to other Schools minimum A Grade Chemistry A Level/Higher/IB
Additional Costs	Purchase of a laboratory coat.

Information for Visiting Students
Pre-requisites	Minimum A Grade Chemistry A Level/Higher/IB. Visiting students are advised that this course is at the second year university academic level and has a pre-requisite of 40 credits in first year chemistry/biological chemistry or equivalent for UoE students. Visiting students must have a sound knowledge of chemistry.
High Demand Course?	Yes

Course Delivery Information

Academic year 2024/25, Available to all students (SV1)		Quota: 192
Course Start	Semester 1
Timetable	Timetable
Learning and Teaching activities (Further Info)	Total Hours: 200 ( Lecture Hours 33, Seminar/Tutorial Hours 5, Supervised Practical/Workshop/Studio Hours 23, Programme Level Learning and Teaching Hours 4, Directed Learning and Independent Learning Hours 135 )
Assessment (Further Info)	Written Exam 70 %, Coursework 30 %, Practical Exam 0 %
Additional Information (Assessment)	3-hour Written Examination in December diet (70% of overall mark) + Laboratory (30% of overall mark)
Feedback	Each lecture course unit has an associated examples class. This will provide students with practice at problem-solving and tackling exam-like questions. It is also an opportunity for students to discuss any issues pertaining to the lecture course. Feedback is also given for each of the 4 laboratory reports.
Exam Information
Exam Diet	Paper Name		Hours & Minutes
Main Exam Diet S1 (December)	Biological Chemistry 2 SV1		3:180
Resit Exam Diet (August)	Biological Chemistry 2 SV1		3:180

Academic year 2024/25, Part-year visiting students only (VV1)		Quota: 7
Course Start	Semester 1
Timetable	Timetable
Learning and Teaching activities (Further Info)	Total Hours: 200 ( Lecture Hours 33, Seminar/Tutorial Hours 5, Supervised Practical/Workshop/Studio Hours 23, Programme Level Learning and Teaching Hours 4, Directed Learning and Independent Learning Hours 135 )
Assessment (Further Info)	Written Exam 70 %, Coursework 30 %, Practical Exam 0 %
Additional Information (Assessment)	3-hour Written Examination in December diet (70% of overall mark) + Laboratory (30% of overall mark)
Feedback	Each lecture course unit has an associated examples class. This will provide students with practice at problem-solving and tackling exam-like questions. It is also an opportunity for students to discuss any issues pertaining to the lecture course. Feedback is also given for each of the 4 laboratory reports.
Exam Information
Exam Diet	Paper Name		Hours & Minutes
Main Exam Diet S1 (December)	Biological Chemistry 2 VV1		:180
Resit Exam Diet (August)	Biological Chemistry 2 VV1		:180

Learning Outcomes
On completion of this course, the student will be able to: Appreciate how to expand their chemical knowledge as applied to biological chemistry through various modes of teaching and learning. Understand and describe fundamental aspects of biological chemistry across three broad areas (organic, physical and inorganic). Specifically understand the structure of biological molecules (including nucleic acids, lipids and proteins); the structure and function of post-translational modifications of proteins; the concepts of kinetics and thermodynamics and the use of enzyme assays to generate such data; the biosynthesis of natural products; the chemical biology of organic cofactors; biological inorganic chemistry. Take part in discussions in the tutorials and lab classes. Record, analyse and interpret experimental data and relate to core material. Carry out laboratory experiments safely across the organic, physical and inorganic areas. Prepare clear, well-structured lab reports. Use external material (www, books, research literature) to answer laboratory-associated questions.

Reading List
Any good biochemistry textbook; e.g. Stryer. Organic chemistry covered by McMurry. Post-translational modifications - book by Walsh - published review in Angewandte Chemie. Kinetics/thermodynamics and spectroscopy covered by general chemistry text e.g. Blackman. Reading lists pertaining to each course unit will be given by the lecturers.

Additional Information
Graduate Attributes and Skills	1. Data analysis and processing (Origin, ChemDraw) 2. Written communication (lab reports) 3. Team work (lab) 4. Independent learning (use core lecture material to explore current research areas)
Additional Class Delivery Information	3 x 1-hour lectures every week on Monday, Tuesday and Friday mornings. Examples Classes and Labs are held on Thursdays. All teaching is delivered on King's Buildings Campus.
Keywords	biological chemistry,synthesis and reactivity,enzyme kinetics

Contacts
Course organiser	Dr Chris Mowat Tel: (0131 6)50 4738 Email: C.G.Mowat@ed.ac.uk	Course secretary	Ms Morag Munro Tel: (0131 6) 51 7258 Email: Morag.Munro@ed.ac.uk