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DRPS : Course Catalogue : School of Biological Sciences : Genetics

Undergraduate Course: The Cell Cycle: DNA Replication, Segregation and Checkpoints (GENE10015)

Course Outline
SchoolSchool of Biological Sciences CollegeCollege of Science and Engineering
Credit level (Normal year taken)SCQF Level 10 (Year 4 Undergraduate) AvailabilityNot available to visiting students
SCQF Credits10 ECTS Credits5
SummaryThe purpose of the cell division cycle is to ensure the accurate duplication of the cellular DNA and its partitioning into daughter cells. These lectures deal with the molecular mechanisms involved in the fundamental process of DNA replication and the controls regulating its occurrence during the cell cycles of prokaryotes and eukaryotes. In bacteria, cell growth and cell wall assembly are coordinated with cell cycle progress, and the assembly of a septum cross-wall is essential for cell division. Duplication of the genetic material becomes more complex in eukaryotic cells, as chromosomes are larger and DNA is tightly packed into chromatin. Controls called checkpoints prevent the cell from initiating late cell cycle events until earlier processes have been correctly completed. Failure of these checkpoints in vertebrate cells is implicated in some forms of cancer.
Course description Not entered
Entry Requirements (not applicable to Visiting Students)
Pre-requisites Co-requisites
Prohibited Combinations Other requirements None
Additional Costs Notepads
Course Delivery Information
Academic year 2024/25, Not available to visiting students (SS1) Quota:  0
Course Start Semester 1
Timetable Timetable
Learning and Teaching activities (Further Info) Total Hours: 100 ( Lecture Hours 30, Summative Assessment Hours 2, Programme Level Learning and Teaching Hours 2, Directed Learning and Independent Learning Hours 66 )
Assessment (Further Info) Written Exam 0 %, Coursework 100 %, Practical Exam 0 %
Feedback Not entered
No Exam Information
Learning Outcomes
On completion of this course, the student will be able to:
  1. explain the molecular mechanisms of cell cycle checkpoints and control mechanisms in the context of past and current research field.
  2. summarise and critically discuss research data relevant to the field of the cell cycle.
  3. design experiments to decipher cell cycle control mechanisms.
  4. write short essays that critically discuss a specific question in the cell cycle field, and come up with their own ideas and hypotheses.
  5. extract the key information from a scientific paper and present it in a clear manner to a non-expert audience.
Reading List
None
Additional Information
Graduate Attributes and Skills Not entered
KeywordsGENECellCycl
Contacts
Course organiserDr Adele Marston
Tel: (0131 6)50 7088
Email: adele.marston@ed.ac.uk
Course secretaryMiss Donna Wright
Tel: (0131 6)51 7051
Email: Donna.Wright@ed.ac.uk
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