Postgraduate Course: Introduction to Models of Disease - Bioscience and Ethics (VESC11244)
Course Outline
| School | Royal (Dick) School of Veterinary Studies |
College | College of Medicine and Veterinary Medicine |
| Credit level (Normal year taken) | SCQF Level 11 (Postgraduate) |
Availability | Not available to visiting students |
| SCQF Credits | 20 |
ECTS Credits | 10 |
| Summary | In this course all students will receive a wide-ranging lecture-based teaching covering the major themes of the Programme: Modelling disease; Genome modification; Tissue and cell-based models; Large animal models; and Imaging techniques for one health models of disease. |
| Course description |
Teaching will give in depth understanding of both the bioscience of these topics and its ethical and social implications. Lectures topics will include novel animal models of human disorders generated via genome editing, surgery, gene therapy or transgenesis; development and pre-clinical evaluation of novel therapies and diagnostics; 3Rs approaches to study of disease; understanding gene function in the context of infection or disease via genome-scale mutagenesis; and comparative biology of diseases shared by humans and animals (e.g. tuberculosis, influenza, enteric pathogens). These lectures will highlight the role that one health models of disease have played in advancing knowledge. In alternating week there will be facilitated discussions with members of the Centre for Biomedicine, Self and Society about the ethical issues raised by the bioscience research showcased in the portrait lectures.
Teaching will be delivered in small groups with considerable time allowed for discussion and in-depth exploration of the issues raised.
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Entry Requirements (not applicable to Visiting Students)
| Pre-requisites |
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Co-requisites | |
| Prohibited Combinations | |
Other requirements | None |
Course Delivery Information
| Not being delivered |
Learning Outcomes
On completion of this course, the student will be able to:
- demonstrate knowledge of One Health approaches can be used to generate models applicable to human and animals disease
- appreciate the technological basis for genome modification and gene editing, and the ethical implications of these techniques
- understand how large animal, tissue cell-based models are used to study disease in humans and animals
- recognise how bioimaging techniques are used to study One Health models of disease
- appreciate the 3Rs - Replacement, Reduction and Refinement - approach to use of animals in research
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Additional Information
| Graduate Attributes and Skills |
Upon completion of this course students will have developed a wide range of Graduate Attributes and Skills that will contribute to their professional growth as successful researchers and experts in their field.
Through exposure to world-leading research, they are innovative and lifelong learners.
By taking a confident and reflective approach to their learning, they take personal responsibility for pushing their goals and opportunities to grow. |
| Keywords | Modelling disease,Genome modification,Tissue and cell-based models,Large animal models,Imaging |
Contacts
| Course organiser | Prof Jonathan Fitzgerald
Tel: (0131 6)51 9235
Email: Ross.Fitzgerald@ed.ac.uk |
Course secretary | Miss Jennifer Hurst
Tel: (0131 6)51 3685
Email: jennifer.hurst@ed.ac.uk |
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