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DEGREE REGULATIONS & PROGRAMMES OF STUDY 2010/2011
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DRPS : Course Catalogue : School of Biomedical Sciences : Medical Biology (Biomedical Sciences)

Undergraduate Course: Stress and the Brain (MBBM10004)

Course Outline
School School of Biomedical Sciences College College of Medicine and Veterinary Medicine
Course type Standard Availability Not available to visiting students
Credit level (Normal year taken) SCQF Level 10 (Year 4 Undergraduate) Credits 10
Home subject area Medical Biology (Biomedical Sciences) Other subject area None
Course website None Taught in Gaelic? No
Course description This course aims to give students an understanding of the nature, functions and control of the hypothalamo-pituitary-adrenal (HPA) stress axis, and its role in regulating brain function both in the normal state and during adaptation to changes in the internal and external environment.

The objectives are to understand (a) the components of the HPA axis and their interactions in regulating the stress response; (b) the regulation of neuronal and synaptic function in the brain by stress hormones, particularly glucocorticoids; and (c) the role of stress hormones, their receptors and related control elements in specific physiological conditions of adaptation in the brain. Resetting of activity of the stress response axis as a result of early experience, pregnancy and ageing will be discussed. The interactions between the immune system and the stress axis will be considered. Understanding the disorders that are attributable to chronic stress will be a focus for advanced discussion; these include anxiety, depression, impairment of cognitive ability, and altered metabolic regulation and its consequences.

Teaching Methods: The course will include seminars covering the core aspects of the subject. Students will write an essay and take part in 'journal club' type meetings to discuss relevant research papers. Students will be organised into small teams and presented with a number of current research problems in the field. They will be expected to gain an overview of an area, then investigate a specific aspect from the literature and give an argued presentation on published experimental research that addresses the problem. No practical elements.
Entry Requirements
Pre-requisites Co-requisites It is RECOMMENDED that students also take Physiology 3 (BIME09004) OR Brain and Behaviour 3 (BILG09012)
Prohibited Combinations Students MUST NOT also be taking Glucocorticoids in the Brain (NEBM10015)
Other requirements None
Additional Costs None
Course Delivery Information
Not being delivered
Summary of Intended Learning Outcomes
Increased understanding of biological processes.
Detailed learning outcomes will be provided later.
Assessment Information
December Exam 100% Written Examination Duration 2 hrs
Special Arrangements
None
Additional Information
Academic description Not entered
Syllabus Not entered
Transferable skills Not entered
Reading list Not entered
Study Abroad Not entered
Study Pattern Not entered
Keywords Not entered
Contacts
Course organiser Dr Martin Simmen
Tel: (0131 6)51 1773
Email: M.Simmen@ed.ac.uk
Course secretary Ms Lisa Ketchion
Tel: (0131 6)51 1629
Email: Lisa.Ketchion@ed.ac.uk
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copyright 2011 The University of Edinburgh - 31 January 2011 8:00 am