Postgraduate Course: Commercial Aspects of Drug Discovery (PGBI11049)
Course Outline
| School |
School of Biological Sciences |
College |
College of Science and Engineering |
| Course type |
Standard |
Availability |
Available to all students |
| Credit level (Normal year taken) |
SCQF Level 11 (Postgraduate) |
Credits |
10 |
| Home subject area |
Postgraduate |
Other subject area |
None |
| Course website |
None
|
Taught in Gaelic? |
No |
| Course description |
This course gives the student a general, illustrated overview over the different stages in drug design from the industrial perspective. The considerations and practicalities of selecting, initiating and running a drug discovery programme will be covered as well as the key topic of finding a lead compound that exhibits the desired biological activity with the highest possible benefits. This course is clearly distinct from the structure-based drug design compulsory module where the topic of rational drug design is covered in detail. The course includes industrial visits and visits from industrial scientists. |
Entry Requirements
| Pre-requisites |
It is RECOMMENDED that students have passed
Pharmacology (DENT11002)
|
Co-requisites |
|
| Prohibited Combinations |
|
Other requirements |
None
|
| Additional Costs |
None |
Information for Visiting Students
| Pre-requisites |
None |
| Displayed in Visiting Students Prospectus? |
Yes |
Course Delivery Information
|
| Delivery period: 2010/11 Semester 2, Available to all students (SV1)
|
WebCT enabled: Yes |
Quota: None |
| Location |
Activity |
Description |
Weeks |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
| External To University | Lecture | | 1-11 | 09:00 - 17:00 | | | | |
| First Class |
Week 1, Monday, 14:00 - 15:50, Zone: King's Buildings. Darwin 315 |
| No Exam Information |
Summary of Intended Learning Outcomes
Appreciation of various aspects in the drug discovery process, including industrial considerations and the drug testing process.
- Principles of drug action, general topics in medicinal chemistry
- Industrial considerations for picking a drug area (Existing therapies, commercial aspects, etc)
- Lead compounds
Gene profiling
Natural products
Synthetic products
Screening methods: Assays, Microarrays
Libraries, combinatorial chemistry
Rational design (structure-based drug design, etc)
- Assessing lead compounds
Absorption, distribution, metabolism, excretion and toxicology (ADME/tox)
In vitro and in vivo testing
- Drug delivery
- Clinical trials
- Production and marketing
Drug synthesis
Marketing, social, moral aspects
Patents
|
Assessment Information
| A 'Blog' account of each of the sessions. PLUS an essay covering synthesis of drug commercialisation obtained from the visits and outside reading. |
Special Arrangements
| None |
Additional Information
| Academic description |
Not entered |
| Syllabus |
Not entered |
| Transferable skills |
Not entered |
| Reading list |
Not entered |
| Study Abroad |
Not entered |
| Study Pattern |
Not entered |
| Keywords |
Not entered |
Contacts
| Course organiser |
Prof Malcolm Walkinshaw
Tel: (0131 6)50 3719
Email: M.Walkinshaw@ed.ac.uk |
Course secretary |
Miss Vicky Mactaggart
Tel: (0131 6)51 7052
Email: Vicky.Mactaggart@ed.ac.uk |
|
copyright 2011 The University of Edinburgh -
31 January 2011 8:05 am
|
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