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DRPS : Course Catalogue : School of Engineering : Postgrad (School of Engineering)

Postgraduate Course: Measurement Methods in Hard/Soft Tissues and Fluids (MSc) (PGEE11056)

Course Outline
School School of Engineering College College of Science and Engineering
Course type Standard Availability Not available to visiting students
Credit level (Normal year taken) SCQF Level 11 (Postgraduate) Credits 10
Home subject area Postgrad (School of Engineering) Other subject area None
Course website None Taught in Gaelic? No
Course description This module covers the basic underpinning real-world measurement of the properties of biological tissues. This includes methods used to obtain data on the relevant physical properties of biological materials, including the following:

&· Mechanical properties using stress-strain measurement.
&· Fluid properties with viscometry.
&· Electrical properties (conductivity) and imaging electrical impedance tomography, and microscopy of neuron activity.
&· Thermodynamic properties (thermal conductivity, specific heat capacity) and thermal imaging.
&· Optical properties (refractive index, scattering, crystallinity) and microscopy of ordered protein structures (collagen, elastin).
&· Material/chemical properties with Raman spectroscopy
Methods of measurement of forces on micro-tissues will be covered using Atomic Force Microscopy (also used to image stiffness, adhesion, and friction on the nanoscale).

In vivo imaging techniques will be discussed: ultrasound (bulk modulus, Doppler: blood flow), x-rays (bone density, absorption in tumors), and laser Doppler imaging.

The module will also cover the use of tools used in orthopaedic and cardiovascular surgery.
Entry Requirements
Pre-requisites Co-requisites
Prohibited Combinations Other requirements None
Additional Costs None
Course Delivery Information
Not being delivered
Summary of Intended Learning Outcomes
The student will be exposed to a wide range of techniques employed for measuring mechanical, material, thermal, optical, electrical and fluid properties in medical diagnosis and biological research.

Lectures will address which methods are used to acquire data and images on this range of properties, and will concentrate on both theory, and practicalities of each technique.

Insights from the Engineering, Medical and Biological perspectives will be acquired from a series of practical demonstrations of measurements of the vast majority of these properties.
Assessment Information
Examination (100%)
Special Arrangements
None
Additional Information
Academic description Not entered
Syllabus Lectures:

1. Introduction to measurement using instruments
2. Measurements of distance/geometry/structure
3. Measurement of strain/stress
4. Atomic Force Microscopy
5. Fluid properties and viscometry
6. Optical measurements including Raman spectroscopy
7. Electrical and Thermal properties
8. In vivo measurement of mechanical & fluid properties
9. Tools for performing orthopaedic surgery (guest)
10. Tools for performing cardiovascular surgery (guest)

Demonstrations:

1. Kings Buildings demonstration (3 hours)
Raman spectroscopy, AFM, Viscometer, Tensile testing
2. Chancellors Building am (measurement) (3 hours)
tensile testing, thermal camera, flow phantoms, navigation systems
3. Chancellors Building pm (invasive) (3 hours)
orthopaedic tools, cardiovascular tools, ultrasonic cutting, comminutor
Transferable skills Not entered
Reading list Not entered
Study Abroad Not entered
Study Pattern Not entered
Keywords Measurement, atomic force microscopy (AFM), tensile testing, raman spectroscopy, viscometry, electro
Contacts
Course organiser Dr Andrew Downes
Tel: (0131 6)51 7072
Email: Andy.Downes@ed.ac.uk
Course secretary Mrs Kim Orsi
Tel: (0131 6)50 5687
Email: Kim.Orsi@ed.ac.uk
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copyright 2011 The University of Edinburgh - 31 January 2011 8:05 am