Undergraduate Course: Neurotransmitters In Action (BIME10008)
Course Outline
| School | School of Biomedical Sciences |
College | College of Medicine and Veterinary Medicine |
| Course type | Standard |
Availability | Not available to visiting students |
| Credit level (Normal year taken) | SCQF Level 10 (Year 4 Undergraduate) |
Credits | 20 |
| Home subject area | Biomedical Sciences |
Other subject area | None |
| Course website |
None |
Taught in Gaelic? | No |
| Course description | Knowledge of the cellular and molecular mechanisms that underlie excitatory and inhibitory synaptic transmission is fundamental to our understanding of the function of the nervous system in health and disease. Through the evaluation of complementary experimental and quantitative approaches this course addresses the physiological, pharmacological and molecular biological mechanisms that relate to pre- and post-synaptic actions of neurotransmitters. Ligand-gated and metabotropic receptor function will be analysed in terms of receptor structure/function relationships; the dependent intracellular signalling pathways; the modulation of ion channels involved in regulating neuronal excitability; and the mechanisms by which neurotransmitters modulate either their own release or that of other neurotransmitters. |
Course Delivery Information
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| Delivery period: 2014/15 Semester 1, Not available to visiting students (SS1)
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Learn enabled: Yes |
Quota: None |
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Web Timetable |
Web Timetable |
| Course Start Date |
15/09/2014 |
| Breakdown of Learning and Teaching activities (Further Info) |
Total Hours:
200
(
Lecture Hours 40,
Programme Level Learning and Teaching Hours 4,
Directed Learning and Independent Learning Hours
156 )
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| Additional Notes |
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| Breakdown of Assessment Methods (Further Info) |
Written Exam
70 %,
Coursework
30 %,
Practical Exam
0 %
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| No Exam Information |
Summary of Intended Learning Outcomes
Demonstrate knowledge and understanding of;
¿ neurotransmitter actions on ligand-gated and metabotropic receptors,
¿ downstream mechanisms of intracellular signalling and postsynaptic responses,
¿ mechanisms controlling of neurotransmitter release from presynaptic neurones,
¿ the involvement of neurotransmitters, receptors, transporters and dependent intracellular signalling in selected neurodegenerative diseases, neurological dysfunctions, and psychiatric illnesses.
Demonstrate an ability to:
¿ discuss and critically evaluate the different experimental and quantitative methodologies that have expanded our knowledge of neurotransmitter action,
¿ interpret and evaluate information in original articles and figures,
¿ draw together information from different approaches to identify the underlying mechanisms that might contribute to selected neurodegenerative diseases, neurological dysfunctions, or psychiatric illnesses.
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Assessment Information
30% ICA
70% Written Exam
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Special Arrangements
| None |
Additional Information
| Academic description |
Co course organisers: M Jackson, P Larkman, RR Ribchester and DJ Wyllie |
| Syllabus |
Not entered |
| Transferable skills |
Not entered |
| Reading list |
Not entered |
| Study Abroad |
Not entered |
| Study Pattern |
Not entered |
| Keywords | Synapses, synaptic transmission, neurotransmitters, receptors, signalling, second messengers, gene e |
Contacts
| Course organiser | Dr Mandy Jackson
Tel: (0131 6)50 7518
Email: Mandy.Jackson@ed.ac.uk |
Course secretary | Ms Lisa Ketchion
Tel: (0131 6)51 1629
Email: Lisa.Ketchion@ed.ac.uk |
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