Undergraduate Course: Neurotransmitters In Action (BIME10008)
|School||Deanery of Biomedical Sciences
||College||College of Medicine and Veterinary Medicine
|Credit level (Normal year taken)||SCQF Level 10 (Year 4 Undergraduate)
||Availability||Not available to visiting students
|Summary||Knowledge of the cellular and molecular mechanisms that underlie excitatory and inhibitory synaptic transmission is fundamental to our understanding of the function of the nervous system in health and disease. Through the evaluation of complementary experimental and quantitative approaches this course addresses the physiological, pharmacological and molecular biological mechanisms that relate to pre- and post-synaptic actions of neurotransmitters. Ligand-gated and metabotropic receptor function will be analysed in terms of receptor structure/function relationships; the dependent intracellular signalling pathways; the modulation of ion channels involved in regulating neuronal excitability; and the mechanisms by which neurotransmitters modulate either their own release or that of other neurotransmitters.
The course will comprise of computer workshops, lectures and student presentations. Students are expected to engage in discussion throughout the course.
Co course organisers: M Jackson, P Larkman, RR Ribchester and DJ Wyllie
Course Delivery Information
|Academic year 2015/16, Not available to visiting students (SS1)
|Learning and Teaching activities (Further Info)
Lecture Hours 32,
Seminar/Tutorial Hours 4,
Feedback/Feedforward Hours 1,
Formative Assessment Hours 1,
Summative Assessment Hours 3,
Revision Session Hours 6,
Programme Level Learning and Teaching Hours 4,
Directed Learning and Independent Learning Hours
|Assessment (Further Info)
|Additional Information (Assessment)
70% Written Exam
||Feedback will be available throughout the course in many forms:
-Written feedback on ICA component outlining the general scope of poster content will be given
-Verbal feedback on layout and content of draft poster will be available
-Feedback from course lecturers on your presentations will be available
-Written feedback on poster presentation and ability to answer questions will be given
-End-of-course feedback session to go over exam questions and techniques as well as specific student questions about topics has been timetabled for students
-Feedback from the exam will be made available.
||Hours & Minutes
|Main Exam Diet S1 (December)||Neurotransmitters in Action||2:00|
On completion of this course, the student will be able to:
- Demonstrate knowledge and understanding of; neurotransmitter actions on ligand-gated and metabotropic receptors, downstream mechanisms of intracellular signalling and postsynaptic responses, mechanisms controlling of neurotransmitter release from presynaptic neurones, the involvement of neurotransmitters, receptors, transporters and dependent intracellular signalling in selected neurodegenerative diseases, neurological dysfunctions, and psychiatric illnesses.
- Demonstrate an ability to: discuss and critically evaluate the different experimental and quantitative methodologies that have expanded our knowledge of neurotransmitter action, interpret and evaluate information in original articles and figures, draw together information from different approaches to identify the underlying mechanisms that might contribute to selected neurodegenerative diseases, neurological dysfunctions, or psychiatric illnesses.
|Byrne, J.H. and Roberts, J.L. (2009) From Molecules to Networks: an introduction to cellular and molecular neuroscience. 2nd edn. Academic Press|
Nicholls, J.G. et al (2012) From Neuron to Brain. 5th edn. Sinauer.
|Graduate Attributes and Skills
|Course organiser||Dr Mandy Jackson
Tel: (0131 6)50 7518
|Course secretary||Mr Kevin Mcarthur
Tel: (0131 6)51 1824
© Copyright 2015 The University of Edinburgh - 18 January 2016 3:30 am