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DEGREE REGULATIONS & PROGRAMMES OF STUDY 2015/2016

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DRPS : Course Catalogue : Deanery of Biomedical Sciences : Biomedical Sciences

Undergraduate Course: Diagnostics and therapeutics for infectious disease (BIME10025)

Course Outline
SchoolDeanery of Biomedical Sciences CollegeCollege of Medicine and Veterinary Medicine
Credit level (Normal year taken)SCQF Level 10 (Year 4 Undergraduate) AvailabilityNot available to visiting students
SCQF Credits20 ECTS Credits10
SummaryLectures: This course will focus on applied and translational aspects of infectious disease research. The course emphasises modern research trends for the in diagnostics and therapeutics which are being developed to improve the detection, prevention and treatment of infectious disease. This course will cover 4 main themes:

*Pathogen diagnostics:
*Challenges of pathogen detection and surveillance
*Principles of pathogen diagnostics
*Molecular diagnostics for infectious disease
*Case study infection diagnostics in the clinic
*The role of the host response and biomarkers as a diagnostic tool for infection and disease

*Drugs targeting pathogens:
*Principles, challenges and opportunities of drug therapeutics for infectious disease
*Case studies covering:
*Viral disease
*Bacteria and the antibiotic crisis
*Parasitic and fungal disease

*Vaccines:
*Principles of vaccinology
*Challenges and opportunities
*Case studies covering:
*Viral, bacterial and parasitic disease

*Immunotherapy for infectious disease
*Principles of immune modulation and biologics for the treatment of infectious disease
*Manipulating T-cells and dendritic cells
*Antibody technologies
*Manipulating the immune response for bacterial disease
*Manipulating the immune response for viral disease

A series of in-class sessions will be held to provide formative feedback for the summative assessments of the course.
Course description Not entered
Entry Requirements (not applicable to Visiting Students)
Pre-requisites Students MUST have passed: Medical Microbiology 3 (BIME09002) AND Biomedical Sciences 3 (BIME09008)
It is RECOMMENDED that students have passed Clinical Immunology & Haematology 3A (MSBM09005) OR Immunology 3 (BILG09007)
Co-requisites
Prohibited Combinations Other requirements Students who are either enrolled on the BSc (Hons) Medical Sciences, or who spent their third year abroad, or who are taking an intercalated year, are exempt from the requirement to have taken and passed Biomedical Sciences 3.
Course Delivery Information
Academic year 2015/16, Not available to visiting students (SS1) Quota:  0
Course Start Semester 1
Timetable Timetable
Learning and Teaching activities (Further Info) Total Hours: 200 ( Lecture Hours 32, Feedback/Feedforward Hours 4, Formative Assessment Hours 4, Summative Assessment Hours 6, Revision Session Hours 2, Programme Level Learning and Teaching Hours 4, Directed Learning and Independent Learning Hours 148 )
Assessment (Further Info) Written Exam 60 %, Coursework 40 %, Practical Exam 0 %
Additional Information (Assessment) 40% ICA incorporating an oral presentation and poster presentation related to a course topic
60% Exam
Feedback Feedback will be available throughout the course in many forms:
*Feedback from course organiser and peers on your poster presentations
*Mid-course feedback session, as well as several sessions later in the course to go over
exam questions and techniques as well as specific student questions about topics has been
timetabled for students
*Feedback from the exam will be made available; please contact BMTO staff for more
information about how and when this will be done
Exam Information
Exam Diet Paper Name Hours & Minutes
Main Exam Diet S1 (December)Diagnostics and therapeutics for infectious disease1:30
Learning Outcomes
On completion of this course, the student will be able to:
  1. Explain and identify the importance of applied and translational aspects of infectious disease research, especially in relation to healthcare systems
  2. Explain the main techniques for pathogen diagnostics ranging from established approaches to modern molecular based systems
  3. Explain the principles and importance of drug therapeutics for infectious disease
  4. Explain the principles of immunotherapy and how this is applied as a therapeutic for infectious disease
  5. Demonstrate the ability to illustrate and present information regarding a particular infectious disease in poster format and critically analyse the scientific literature through the study of key papers.
Reading List
Mims CA, Nash A & Stephen J (2001). Mims┐ pathogenesis of infectious disease, 5th edn, Elsevier. ISBN: 9780124982642

Goering R, Dockrell H, Zuckerman M, Roitt I & Chiodini P (2012). Mims┐ medical microbiology, 5th edn, Saunders. ISBN: 9780723436010

Murray PR, Rosenthal KS & Pfaller MA (2009). Medical microbiology 7th edn, Mosby Elsevier. ISBN: 9780323086929

Thomson C, Miles R & Amyes SBG (1996). Antimicrobial chemotherapy, Informa. ISBN: 9781853173899

Salyers AA, Wilson BA, Whitt DD & Winkler ME (2010). Bacterial pathogenesis: a molecular approach, 3rd edn, ASM press. ISBN: 9781555814182

Flint SJ, Enquist LW, Krug RM, Racaniello VR & Skalka AM (2009). Principles of virology, 3rd edn,. vol 1 Molecular biology ISBN: 9781555814793, vol 2 Pathogenesis and control IBN: 9781555814809, ASM press

Murphy K (2011). Janeway┐s immunobiology, 8th edn, Garland Science. ISBN:9780815342434
Additional Information
Graduate Attributes and Skills Not entered
KeywordsD&TID
Contacts
Course organiserDr Simon Talbot
Tel: (0131 6)50 7938
Email: s.talbot@ed.ac.uk
Course secretaryMs Tracy Noden
Tel: (0131 6)50 3717
Email: Tracy.Noden@ed.ac.uk
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