Undergraduate Course: Diagnostics and therapeutics for infectious disease (BIME10025)
Course Outline
| School | Deanery of Biomedical Sciences | 
College | College of Medicine and Veterinary Medicine | 
 
| Credit level (Normal year taken) | SCQF Level 10 (Year 4 Undergraduate) | 
Availability | Not available to visiting students | 
 
| SCQF Credits | 20 | 
ECTS Credits | 10 | 
 
 
| Summary | Lectures: This course will focus on applied and translational aspects of infectious disease research. The course emphasises modern research trends for the in diagnostics and therapeutics which are being developed to improve the detection, prevention and treatment of infectious disease.  This course will cover 4 main themes: 
 
*Pathogen diagnostics: 
	*Challenges of pathogen detection and surveillance 
	*Principles of pathogen diagnostics 
	*Molecular diagnostics for infectious disease 
	*Case study infection diagnostics in the clinic 
	*The role of the host response and biomarkers as a diagnostic tool for infection and disease 
 
*Drugs targeting pathogens: 
	*Principles, challenges and opportunities of drug therapeutics for infectious disease 
	*Case studies covering: 
	*Viral disease 
	*Bacteria and the antibiotic crisis 
	*Parasitic and fungal disease 
 
*Vaccines: 
	*Principles of vaccinology 
	*Challenges and opportunities 
	*Case studies covering: 
	*Viral, bacterial and parasitic disease 
   
*Immunotherapy for infectious disease  
	*Principles of immune modulation and biologics for the treatment of infectious disease 
	*Manipulating T-cells and dendritic cells 
	*Antibody technologies 
	*Manipulating the immune response for bacterial disease 
	*Manipulating the immune response for viral disease 
 
A series of in-class sessions will be held to provide formative feedback for the summative assessments of the course. | 
 
| Course description | 
    
    Not entered
    
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Course Delivery Information
 |  
| Academic year 2015/16, Not available to visiting students (SS1) 
  
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Quota:  0 | 
 
| Course Start | 
Semester 1 | 
 
Timetable  | 
	
Timetable | 
| Learning and Teaching activities (Further Info) | 
 
 Total Hours:
200
(
 Lecture Hours 32,
 Feedback/Feedforward Hours 4,
 Formative Assessment Hours 4,
 Summative Assessment Hours 6,
 Revision Session Hours 2,
 Programme Level Learning and Teaching Hours 4,
Directed Learning and Independent Learning Hours
148 )
 | 
 
| Assessment (Further Info) | 
 
  Written Exam
60 %,
Coursework
40 %,
Practical Exam
0 %
 | 
 
 
| Additional Information (Assessment) | 
40% ICA incorporating an oral presentation and poster presentation related to a course topic 
60% Exam | 
 
| Feedback | 
Feedback will be available throughout the course in many forms: 
*Feedback from course organiser and peers on your poster presentations 
*Mid-course feedback session, as well as several sessions later in the course to go over 
exam questions and techniques as well as specific student questions about topics has been 
timetabled for students 
*Feedback from the exam will be made available; please contact BMTO staff for more 
information about how and when this will be done | 
 
| Exam Information | 
 
    | Exam Diet | 
    Paper Name | 
    Hours & Minutes | 
    
	 | 
  
| Main Exam Diet S1 (December) | Diagnostics and therapeutics for infectious disease | 1:30 |  |  
 
Learning Outcomes 
    On completion of this course, the student will be able to:
    
        - Explain and identify the importance of applied and translational aspects of infectious disease research, especially in relation to healthcare systems
 - Explain the main techniques for pathogen diagnostics ranging from established approaches to modern molecular based systems
 - Explain the principles and importance of drug therapeutics for infectious disease
 - Explain the principles of immunotherapy and how this is applied as a therapeutic for infectious disease
 - Demonstrate the ability to illustrate and present information regarding a particular infectious disease in poster format and critically analyse the scientific literature through the study of key papers.
 
     
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Reading List 
Mims CA, Nash A & Stephen J (2001). Mims¿ pathogenesis of infectious disease, 5th edn, Elsevier. ISBN: 9780124982642 
 
Goering R, Dockrell H, Zuckerman M, Roitt I &  Chiodini P (2012). Mims¿ medical microbiology, 5th edn, Saunders.  ISBN: 9780723436010 
 
Murray PR, Rosenthal KS & Pfaller MA (2009). Medical microbiology 7th edn, Mosby Elsevier. ISBN: 9780323086929 
 
Thomson C, Miles R & Amyes SBG (1996). Antimicrobial chemotherapy, Informa. ISBN: 9781853173899 
 
Salyers AA, Wilson BA, Whitt DD & Winkler ME (2010).  Bacterial pathogenesis: a molecular approach, 3rd edn, ASM press. ISBN: 9781555814182 
 
Flint SJ, Enquist LW, Krug RM, Racaniello VR & Skalka AM  (2009).  Principles of virology,   3rd edn,. vol 1 Molecular biology ISBN: 9781555814793, vol 2 Pathogenesis and control IBN: 9781555814809, ASM press 
 
Murphy K  (2011).  Janeway¿s immunobiology, 8th edn, Garland Science.  ISBN:9780815342434 |   
 
Additional Information
| Graduate Attributes and Skills | 
Not entered | 
 
| Keywords | D&TID | 
 
 
Contacts 
| Course organiser | Dr Simon Talbot 
Tel: (0131 6)50 7938 
Email: s.talbot@ed.ac.uk | 
Course secretary | Ms Tracy Noden 
Tel: (0131 6)50 3717 
Email: Tracy.Noden@ed.ac.uk | 
   
 
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© Copyright 2015 The University of Edinburgh -  18 January 2016 3:31 am 
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