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DRPS : Course Catalogue : Deanery of Biomedical Sciences : Microbiology and Infection (Biomedical Sciences)

Undergraduate Course: Host-pathogen interactions in Infectious Disease (MIBM10052)

Course Outline
SchoolDeanery of Biomedical Sciences CollegeCollege of Medicine and Veterinary Medicine
Credit level (Normal year taken)SCQF Level 10 (Year 4 Undergraduate) AvailabilityNot available to visiting students
SCQF Credits20 ECTS Credits10
SummaryLectures: This course focuses on fundamental aspects of pathogen-host interactions and covers the biological mechanisms and processes which lead to pathogenesis and disease following infection. There is an emphasis on the application of modern research methods and approaches in this field. This course comprises three main themes:

* Experimental approaches to study host-pathogen interactions
* Pathobiology of infection
* Pathogen epidemiology and evolution

Tutorials: A series of tutorials will cover essay, abstract and report writing, scientific techniques, presentation skills, scientific calculations and statistics, and the critical analysis of scientific papers. The tutorials will provide important formative feedback/forward for assignments and activities in the course as a whole.
Course description Not entered
Entry Requirements (not applicable to Visiting Students)
Pre-requisites Co-requisites
Prohibited Combinations Other requirements None
Course Delivery Information
Academic year 2015/16, Not available to visiting students (SS1) Quota:  None
Course Start Full Year
Timetable Timetable
Learning and Teaching activities (Further Info) Total Hours: 200 ( Lecture Hours 30, Seminar/Tutorial Hours 10, External Visit Hours 21, Feedback/Feedforward Hours 5, Formative Assessment Hours 3, Summative Assessment Hours 5, Revision Session Hours 2, Programme Level Learning and Teaching Hours 4, Directed Learning and Independent Learning Hours 120 )
Assessment (Further Info) Written Exam 35 %, Coursework 65 %, Practical Exam 0 %
Additional Information (Assessment) 15% ICA Semester 1: 1500 word essay
50% ICA Semester 2: Scientific literature Interpretation test; a series of comprehension questions on a scientific paper. The paper will have the title and abstract removed. The students will also be required to write a suitable abstract and title.
35% Exam
Feedback Feedback will provided for the in-course assessments and, upon request, for the exam.
Exam Information
Exam Diet Paper Name Hours & Minutes
Main Exam Diet S2 (April/May)2:00
Learning Outcomes
On completion of this course, the student will be able to:
  1. Explain and critically assess experimental approaches to study Microbial pathogenesis
  2. Explain the survival strategies of bacterial, viral or parasitic pathogens in the host
  3. Explain the host immune response to pathogens and how pathogens can overcome this
  4. Identify the different host systems affected by pathogens
  5. Recognise the importance of the evolution of pathogens and virulence
Reading List
The following books are recommended as background reading and general reference texts for the Infectious Diseases honours programme:

Mims CA, Nash A & Stephen J (2001). Mims' pathogenesis of infectious disease, 5th edn, Elsevier. ISBN: 9780124982642

Goering R, Dockrell H, Zuckerman M, Roitt I & Chiodini P (2012). Mims' medical microbiology, 5th edn, Saunders. ISBN: 9780723436010

Murray PR, Rosenthal KS & Pfaller MA (2009). Medical microbiology 7th edn, Mosby Elsevier. ISBN: 9780323086929

Thomson C, Miles R & Amyes SBG (1996). Antimicrobial chemotherapy, Informa. ISBN: 9781853173899

Salyers AA, Wilson BA, Whitt DD & Winkler ME (2010). Bacterial pathogenesis: a molecular approach, 3rd edn, ASM press. ISBN: 9781555814182

Flint SJ, Enquist LW, Krug RM, Racaniello VR & Skalka AM (2009). Principles of virology, 3rd edn, vol 1 Molecular biology ISBN: 9781555814793, vol 2 Pathogenesis and control IBN: 9781555814809, ASM press

Murphy K (2011). Janeway's immunobiology, 8th edn, Garland Science. ISBN:9780815342434

You are expected to be familiar with material covered in previous years; make sure you read your relevant lecture notes from previous years to refresh your memory.
Additional Information
Graduate Attributes and Skills Not entered
Course organiserDr Douglas Roy
Tel: (0131) 242 6279
Course secretaryMs Tracy Noden
Tel: (0131 6)50 3717
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