Postgraduate Course: Medicinal Chemistry for MSc Drug Discovery and Translational Biology (PGBI11032)
Course Outline
| School | School of Biological Sciences |
College | College of Science and Engineering |
| Credit level (Normal year taken) | SCQF Level 11 (Postgraduate) |
Availability | Available to all students |
| SCQF Credits | 20 |
ECTS Credits | 10 |
| Summary | Based on U01234
A lecture course covering instruction in both the theory and application of medicinal chemistry. The course comprises individual lectures courses on: Metals in Medicine, Nucleic Acids, Medicinal Chemistry and Industrial Medicinal Chemistry. Either the Level 10 or Level 11 version of this course (as specified in the degree programme tables) is a compulsory requirement for Year 4/5 students on degrees in Medicinal and Biological Chemistry, but can be taken by Year 4/5 students on any Chemistry degree programme. |
| Course description |
Not entered
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Entry Requirements (not applicable to Visiting Students)
| Pre-requisites |
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Co-requisites | |
| Prohibited Combinations | |
Other requirements | None |
Information for Visiting Students
| Pre-requisites | None |
Course Delivery Information
| Not being delivered |
Learning Outcomes
At the end of this course students will be able to:
- describe the biomedical periodic table and the uses of metals in medicine
- show an understanding of the biological significance of RNA and DNA
- show a basic understanding of oligonucleotide chemistry and how it relates to therapeutic and diagnostic applications
- show understanding of rational approaches towards the design of important drugs and the biological implications of such therapeutic agents including the use of enzymes to inhibit protein processing as a concept for the design of new pharmaceuticals
- describe common routes of administration of drugs and drug delivery systems
- describe common metabolic pathways and how they may be exploited in the design of drugs, prodrugs and soft drugs
- describe the basic body functions controlled by hormonal steroids and also how steroids are exploited for non-hormonal uses, particularly neuromuscular blocking agents
- discuss the therapeutic potential for GABAA receptor modulators with particular reference to general anaesthetics including steroids
- discuss the importance of new highspeed technologies for the generation of lead compounds and structure-activity relationships, in particular combinatorial chemistry, high throughput screening and automation
- show understanding of the biological importance of opioids as analgesics
Learning outcomes specific to attainment of a pass at Level 11 include:
- ability to integrate all, or most, of the main areas of the course
- development of original and creative responses to problems and issues within the course
- application of critical analysis, evaluation and synthesis to issues at the forefront of the subject area
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Additional Information
| Graduate Attributes and Skills |
Not entered |
| Keywords | Not entered |
Contacts
| Course organiser | Dr Paul Taylor
Tel: (0131 6)50 7058
Email: p.taylor@ed.ac.uk |
Course secretary | Miss Vicky Mactaggart
Tel: (0131 6)51 7052
Email: Vicky.Mactaggart@ed.ac.uk |
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