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DEGREE REGULATIONS & PROGRAMMES OF STUDY 2015/2016

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DRPS : Course Catalogue : School of Biological Sciences : Postgraduate

Postgraduate Course: Modelling Metabolic Pathways (PGBI11080)

Course Outline
SchoolSchool of Biological Sciences CollegeCollege of Science and Engineering
Credit level (Normal year taken)SCQF Level 11 (Postgraduate) AvailabilityNot available to visiting students
SCQF Credits10 ECTS Credits5
Summary**Online Distance Learning Course**

All cells rely on a complex interacting network of numerous metabolic pathways. Each pathway in turn requires the concerted and well-regulated action of a team of enzymes. These pathways with their component enzymes frequently make attractive drug targets. Metabolic pathways in the parasitic protist Trypanosoma brucei (the causative agent of African sleeping sickness) will be used to illustrate how a combination of biochemical, genetic, control analysis and computer simulation approaches can be used to obtain useful working models of these pathways.
Course description Not entered
Entry Requirements (not applicable to Visiting Students)
Pre-requisites Co-requisites
Prohibited Combinations Other requirements None
Course Delivery Information
Academic year 2015/16, Not available to visiting students (SS1) Quota:  None
Course Start Semester 2
Course Start Date 16/05/2016
Timetable Timetable
Learning and Teaching activities (Further Info) Total Hours: 100 ( Online Activities 20, Programme Level Learning and Teaching Hours 2, Directed Learning and Independent Learning Hours 78 )
Assessment (Further Info) Written Exam 0 %, Coursework 100 %, Practical Exam 0 %
Additional Information (Assessment) 50 % group assessment (including maximum 20% variation for Peer Assessment of contribution)

50 % electronic portfolio comprising learning log and contribution to Skills Profile
Feedback Not entered
No Exam Information
Learning Outcomes
At the end of this course students should be able to:
Appreciate the variability of metabolic status during different life stages of an organism.
Determine control strengths of individual components of metabolic pathways under defined conditions.
Model how changes in metabolite concentrations will affect flux through a pathway.
Explain why particular enzyme components of a pathway may be better drug targets than others.
Devise strategies to explore possible synergy effects when more than one enzyme is inhibited.
Reading List
None
Additional Information
Graduate Attributes and Skills Not entered
KeywordsMMP
Contacts
Course organiserDr Linda Gilmore
Tel: (0131 6)50 7047
Email: linda.gilmore@ed.ac.uk
Course secretaryMiss Vicky Mactaggart
Tel: (0131 6)51 7052
Email: Vicky.Mactaggart@ed.ac.uk
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