University Homepage
DRPS Homepage
DRPS Search
DRPS Contact
DRPS : Course Catalogue : School of Biological Sciences : Postgraduate

Postgraduate Course: Biophysical Chemistry for MSc Biochemistry (PGBI11107)

Course Outline
SchoolSchool of Biological Sciences CollegeCollege of Science and Engineering
Credit level (Normal year taken)SCQF Level 11 (Postgraduate) AvailabilityAvailable to all students
SCQF Credits10 ECTS Credits5
SummaryThis course deals with the major principles of physics and chemistry that underlie the structures, dynamics and interactions of biological macromolecules. The lectures will detail the structures of biomacromolecules and will provide an overview of many modern biophysical techniques. The workshops will allow students to probe macromolecular structures and to explore how the techniques are applied to biological systems and drug discovery. Techniques covered will include NMR spectroscopy, circular dichroism, light scattering, fluorescence, mass spectrometry and surface plasmon resonance.
Course description Weeks 1-3 Chemistry & Structure of Biomacromolecules
- including proteins, nucleic acids, lipids and carbohydrates

Weeks 4-10 Biophysical Characterisation
- techniques and applications

Week 11 Feedback for essay draft
Week 12 Essay deadline
Entry Requirements (not applicable to Visiting Students)
Pre-requisites Co-requisites
Prohibited Combinations Other requirements None
Information for Visiting Students
High Demand Course? Yes
Course Delivery Information
Academic year 2015/16, Available to all students (SV1) Quota:  None
Course Start Semester 1
Timetable Timetable
Learning and Teaching activities (Further Info) Total Hours: 100 ( Lecture Hours 30, Programme Level Learning and Teaching Hours 2, Directed Learning and Independent Learning Hours 68 )
Assessment (Further Info) Written Exam 0 %, Coursework 100 %, Practical Exam 0 %
Additional Information (Assessment) One essay of 2,000 words on a topic to be agreed between the lecturing staff and the Course Organiser (worth 60%) and an in-course problem (worth 40%).
Feedback Not entered
No Exam Information
Learning Outcomes
On completion of this course, the student will be able to:
  1. Have a good understanding of macromolecular structure, conformational changes, dynamics and interactions.
  2. Be able to use molecular graphics tools to analyse molecular structures.
  3. Be familiar with the basic theory, experimental aspects and data analysis of several modern biophysical techniques.
  4. Be able to explain how specific biophysical techniques can be applied to investigate molecular structure, size, conformation and stability.
  5. Be able to explain how specifice biophysical techniques can be applied to molecular interactions.
Reading List
Recommended Reading (reading an occasional chapter, not for purchase)
Biophysical Chemistry (2nd edition) by A. Cooper, Royal Society of Chemistry 2011
Biophysical Chemistry, volumes 1-3 by C.R. Cantor and P.R. Schimmel, Freeman, 1980
Biophysical Techniques by I.D. Campbell, Oxford University Press, 2012
Physical Chemistry: Principles and Applications in Biological Sciences by I. Tinoco, K. Sauer, J.C. Wang and J.D. Puglisi, Prentice Hall, 2002
Principles of Physical Biochemistry by K.E. van Holde, W.C. Johnson and P.S. Ho, Prentice Hall, 1998.
Additional Information
Graduate Attributes and Skills Not entered
Course organiserDr Janice Bramham
Tel: (0131 6)50 4704
Course secretaryMs Andrea Nichol
Tel: (0131 6)50 8643
Help & Information
Search DPTs and Courses
Degree Programmes
Browse DPTs
Humanities and Social Science
Science and Engineering
Medicine and Veterinary Medicine
Other Information
Combined Course Timetable
Important Information
© Copyright 2015 The University of Edinburgh - 18 January 2016 4:32 am