Undergraduate Course: Gene Expression (MLBI10009)
Course Outline
| School | School of Biological Sciences |
College | College of Science and Engineering |
| Credit level (Normal year taken) | SCQF Level 10 (Year 4 Undergraduate) |
Availability | Not available to visiting students |
| SCQF Credits | 10 |
ECTS Credits | 5 |
| Summary | The aim of these lectures is to familiarise students with the variety of mechanisms responsible for regulating the expression of genetic information at the level transcription and post-transcription mechanisms. Teaching will focus on the organisation and packaging of the genetic material in eukaryotic cells and the implications this has for genetic expression. In addition, basic transcription control mechanisms will be examined in prokaryotes and eukaryotes. RNA processing will be studied at the level of splicing and its importance in the regulation of gene expression will be discussed. The special mechanisms which have evolved to operate within, and to take advantage of, a chromatin context will also be reviewed from a biochemical and developmental perspective. |
| Course description |
Not entered
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Entry Requirements (not applicable to Visiting Students)
| Pre-requisites |
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Co-requisites | |
| Prohibited Combinations | |
Other requirements | None |
| Additional Costs | Notepads |
Course Delivery Information
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| Academic year 2025/26, Not available to visiting students (SS1)
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Quota: 0 |
| Course Start |
Semester 1 |
Timetable |
Timetable |
| Learning and Teaching activities (Further Info) |
Total Hours:
100
(
Lecture Hours 20,
Summative Assessment Hours 2,
Programme Level Learning and Teaching Hours 2,
Directed Learning and Independent Learning Hours
76 )
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| Assessment (Further Info) |
Written Exam
80 %,
Coursework
20 %,
Practical Exam
0 %
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| Additional Information (Assessment) |
Both October In-Course Test and December Exam In-person, computer-based (ExamOnline) |
| Feedback |
Not entered |
| Exam Information |
| Exam Diet |
Paper Name |
Minutes |
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| Main Exam Diet S1 (December) | GENE EXPRESSION | 120 | |
Learning Outcomes
On completion of this course, the student will be able to:
- Understand how the genome is organised and packaged within cells.
- Understand molecular mechanisms involved in transcription, pre-mRNA splicing, RNA translation and RNA decay.
- Appreciate how the aforementioned mechanisms are coordinated to control gene expression.
- Understand research techniques that have been instrumental in developing our current understanding of gene expression.
- Interpret data from the scientific literature in order to draw conclusions about the regulation of gene expression. (6) Use this understanding to design experiments, at least at a general level, to answer specific questions concerning the regulation of gene expression.
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Additional Information
| Graduate Attributes and Skills |
Not entered |
| Keywords | MLBIGeneExpr |
Contacts
| Course organiser | Dr Christopher Sibley
Tel: (0131 6)51 1971
Email: chris.sibley@ed.ac.uk |
Course secretary | Miss Donna Wright
Tel: (0131 6)51 7051
Email: Donna.Wright@ed.ac.uk |
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